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Home > メンバー > 藤井　清永

		藤井　清永
		北海道大学大学院構造生物学研究室特任准教授
		fujii@pharm.hokudai.ac.jp
		薬学博士

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K. Fujii*, S. Nakamura, K. Takahashi, and F. Inagaki:
Systematic Characterization by Mass Spectrometric Analysis of Phosphorylation Sites in IRF-3 Regulatory Domain Activated by IKK-i.
J. Proteomics (2010)

T. Nishimura, M. Nomura, H. Tojo, H. Hamasaki, T. Fukuda, K. Fujii, S. Mikami, Y. Bando, and H. Kato:
Proteomic Analysis of Laser-microdissected Paraffin-embedded Tissues: (2) MRM Assay for Stage-related Proteins upon Non-metastatic Lung Adenocarcinoma.
J. Proteomics (2010)

T. Kawamura, M. Nomura, H. Tojo, K. Fujii, H. Hamasaki, S. Mikami, Y. Bando, H. Kato, and T. Nishimura:
Proteomic Analysis of Laser-microdissected Paraffin-embedded Tissues: (1) Stage-related Protein Candidates upon Non-metastatic Lung Adenocarcinoma.
J. Proteomics (2010)

H. Kawase, K. Fujii*, M. Miyamoto, K. C.Kubota, S. Hirano, S. Kondo, and F. Inagaki:
Differential LC-MS-based Proteomics of Surgical Human Cholangiocarcinoma Tissues.
J. Proteome Res., 8, 4092-4103 (2009)

Y. Suehara, K. Kikuta, R. Nakayama, K. Fujii, H. Ichikawa, T. Shibata, K. Seki, T. Hasegawa, M. Gotoh, N. Tochigi, T. Shimoda, Y. Shimada, T. Sano, Y. Beppu, H. Kurosawa, S. Hirohashi, A. Kawai, and T. Kondo:
Anatomic Site-specific Proteomic Signatures of Gastrointestinal Stromal Tumors.
Proteomics Clin. Appl., 3, 584-596 (2009)

Y. Suehara, K. Kikuta, R. Nakayama, N. Tochigi, K. Seki, H. Ichikawa, K. Fujii, T. Hasegawa, T. Shimoda, H. Kurosawa, H. Chuman, Y. Beppu, A. Kawai, S. Hirohashi, and T. Kondo:
GST-P1 as a Histological Biomarker of Synovial Sarcoma Revealed by Proteomics.
Proteomics Clin. Appl., 3, 623-634 (2009)

M. Yamada, K. Fujii, K. Koyama, S. Hirohashi and T. Kondo:
The Proteomic Profile of Pancreatic Cancer Cell Lines Corresponding to Carcinogenesis and Metastasis.
J. Proteomics Bioinform., 2, 1-18 (2009)

Y. Fujioka, N. N. Noda, K. Fujii, K. Yoshimoto, Y. Ohsumi and F. Inagaki:
In Vitro Reconstitution of Plant ATG8 and ATG12 Conjugation Systems Essential for Autophagy.
J. Biol. Chem., 283, 1921-1928 (2008)

Y. Suehara, T. Kondo, K. Seki, T. Shibata, K. Fujii, M. Gotoh, T. Hasegawa, Y. Shimada, M. Sasako, T. Shimoda, H. Kurosawa, Y. Beppu, A. Kawai and S. Hirohashi:
Pfetin as a Prognostic Biomarker of Gastrointestinal Stromal Tumors Revealed by Proteomics.
Clin. Cancer Res., 14, 1707-1717 (2008)

G. Marko-Varga, A. Ogiwara, T. Nishimura, T. Kawamura, K. Fujii, T. Kawakami, Y. Kyono, H.-K. Tu, H. Anyoji, M. Kanazawa, S. Akimoto, T. Hirano, M. Tsuboi, K. Nishio, S. Hada, H. Jiang, M. Fukuoka, K. Nakata, Y. Nishiwaki, H. Kunito, I. S. Peers, C. G. Harbron, M. C. South, T. Higenbottam, F. Nyberg, S. Kudoh, and H. Kato:
Personalized Medicine and Proteomics: Lessons from Non-Small Cell Lung Cancer.
J. Proteome Res., 6, 2925-2935 (2007)

T. Kakisaka, T. Kondo, T. Okano, K. Fujii, K. Honda, M. Endo, A. Tsuchida, T. Aoki, T. Itoi, F. Moriyasu, T. Yamada, H. Kato, T. Nishimura, S. Todo and S. Hirohashi:
Plasma Proteomics of Pancreatic Cancer Patients by Multi-dimensional Liquid Chromatography and Two-dimensional Difference Gel Electrophoresis (2D-DIGE): Up-regulation of Leucine-rich Alpha-2-glycoprotein in Pancreatic Cancer.
J. Chromatogr. B, 852, 257-267 (2007)

A. Nishizawa, A. B. Arshad, T. Nishizawa, M. Asayama, K. Fujii, T. Nakano, K.-I. Harada and M. Shirai:
Cloning and Characterization of a New Hetero-gene Cluster of Nonribosomal Peptide Synthetase and Polyketide Synthase from the Cyanobacterium Microcystis aeruginosa K-139.
J. Gen. Appl. Microbiol., 53, 17-27 (2007)

T. Okano, T. Kondo, K. Fujii, T. Nishimura, T. Takano, Y. Ohe, K. Tsuta, Y. Matsuno, A. Gemma, H. Kato, S. Kudoh and S. Hirohashi:
Proteomic Signature Corresponding to the Response to Gefitinib (Iressa, ZD1839), an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in Lung Adenocarcinoma.
Clin. Cancer Res., 13, 799-805 (2007)

H. Hatakeyama, T. Kondo, K. Fujii, Y. Nakanishi, H. Kato, S. Fukuda and S. Hirohashi:
Protein Clusters associated with Carcinogenesis, Histological Differentiation and Nodal Metastasis in Esophageal Cancer.
Proteomics, 6, 6300-6316 (2006)

Y. Suehara, T. Kondo, T. Kakisaka, K. Fujii, T. Hasegawa, A. Kawai, K. Seki, Y Beppu, T. Nishimura, H. Kurosawa, and S. Hirohashi:
Proteomic Signatures corresponding to Histological Classification and Grading of Soft-tissue Sarcomas.
Proteomics, 6, 4402-4409 (2006)

T. Okano, T. Kondo, T. Kakisaka, K. Fujii, M. Yamada, H. Kato, T. Nishimura, A. Gemma, S. Kudoh, and S. Hirohashi:
Plasma Proteomics of Lung Cancer by a Linkage of Multi-dimensional Liquid Chromatography and Two-dimensional Difference Gel Electrophoresis.
Proteomics, 6, 3938-3948 (2006)

T. Nishimura, A. Ogiwara, K. Fujii, T. Kawakami, T. Kawamura, H. Anyouji and H. Kato:
Disease Proteomics toward Bedside Reality.
J. Gastroenterol., 40, Suppl 16: 7-13 (2005)

K. Fujii, T. Nakano, M. Kanazawa, S. Akimoto, T. Hirano, H. Kato and T. Nishimura:
Clinical-scale High-throughput Human Plasma Proteome Analysis: Lung Adenocarcinoma.
Proteomics, 5, 1150-1159 (2005)

K. Fujii, T. Nakano, H. Hike, F. Usui, Y. Bando and T. Nishimura:
Fully Automated Online Multi-dimensional Protein Profiling System for Complex Mixtures.
J. Chromatogr. A, 1057, 107-113 (2005)

K. Fujii, T. Nakano, T. Kawamura, F. Usui, Y. Bando, R. Wang and T. Nishimura:
Multidimensional Protein Profiling Technology and Its Application to Human Plasma Proteome.
J. Proteome Res., 3, 712-718 (2004)

Y. Igarashi, Y. Yabuta, A. Sekine, K. Fujii, K.-I. Harada, T. Oikawa, M. Sato, T. Furumai and T. Oki:
Directed Biosynthesis of Fluorinated Pseurotin A, Synerazol and Glitoxin.
J. Antibiotics (Tokyo), 57, 748-754 (2004)

K.-I. Harada, K. Tomita, K. Fujii, K. Masuda, Y. Mikami, K. Yazawa and H. Komaki:
Isolation and Structural Characterization of Siderophores, Madurastatins, Produced by a Pathogenic Actinomadura madurae.
J. Antibiotics (Tokyo), 57, 125-135 (2004)

K.-I. Harada, T. Nakano, K. Fujii and M. Shirai:
Comprehensive Analysis System using LC-MS for the Biosynthetic Study of Peptides Produced by Cyanobacteria.
J. Chromatogr. A, 1033, 107-113 (2004)

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