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Home > メンバー > 藤岡　優子

		藤岡　優子
		北海道大学大学院構造生物学研究室研究員
		fujioka@pharm.hokudai.ac.jp
		薬学修士

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Fujioka Y, Noda NN, Nakatogawa H, Ohsumi Y, Inagaki F.
The dimeric coiled-coil structure of Saccharomyces cerevisiae Atg16 and its functional significance in autophagy.
J Biol Chem, 285, 1508-1515 (2010)

Kabeya Y, Noda NN, Fujioka Y, Suzuki K, Inagaki F, Ohsumi Y.
Characterization of the Atg17-Atg29-Atg31 complex specifically required for starvation-induced autophagy in Saccharomyces cerevisiae.
Biochem Biophys Res Commun. , 389, 612-615 (2009)

Satoo K, Noda NN, Kumeta H, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F.
The structure of Atg4B-LC3 complex reveals the mechanism of LC3-processing and delipidation during autophagy
EMBO J, 28, 1341-1350 (2009)

Noda NN, Kumeta H, Nakatogawa H, Satoo K, Adachi W, Ishii J, Fujioka Y, Ohsumi Y, Inagaki F.
Structural basis of target recognition by Atg8/LC3 during selective autophagy.
Genes Cells, 13, 1211-1218 (2008)

Fujioka Y, Noda NN, Matsushita M, Ohsumi Y, Inagaki F
Crystallization of the coiled-coil domain of Atg16 essential for autophagy
Acta Crystallogr Sect F Struct Biol Cryst Commun., 64, 1046-1048 (2008)

Fujioka Y, Noda NN, Fujii K, Yoshimoto K, Ohsumi Y, Inagaki F.
In vitro reconstitution of plant ATG8 and ATG12 conjugation systems essential for autophagy
J Biol Chem., 283, 1921-1928 (2008)

Noda NN, Fujioka Y, Ohsumi Y, Inagaki F.
Crystallization of the Atg12-Atg5 conjugate bound to Atg16 by the free interface diffusion method.
J Synchrotron Radiat. in press (2007)

Hanada T, Noda NN, Satomi Y, Ichimura Y, Fujioka Y, Takao T, Inagaki F, Ohsumi Y.
The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy.
J Biol Chem., 282, 37298-37302 (2007)

Kimura Y, Nagao A, Fujioka Y, Satou A, Taira T, Iguchi-Ariga SM, Ariga H.
MM-1 facilitates degradation of c-Myc by recruiting proteasome and a novel ubiquitin E3 ligase.
Int J Oncol., 31, 829-836 (2007)

Matsushita M, Suzuki NN, Obara K, Fujioka Y, Ohsumi Y, Inagaki F.
Structure of Atg5.Atg16, a complex essential for autophagy.
J Biol Chem., 282, 6763-6772 (2007)

Yamada Y, Suzuki NN, Hanada T, Ichimura Y, Kumeta H, Fujioka Y, Ohsumi Y, Inagaki F.
The crystal structure of Atg3, an autophagy-related ubiquitin carrier protein (E2) enzyme that mediates Atg8 lipidation.
J Biol Chem., 282, 8036-8043 (2007)

Satoo K, Suzuki NN, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F.
Crystallization and preliminary crystallographic analysis of human Atg4B-LC3 complex.
Acta Crystallograph Sect F Struct Biol Cryst Commun., 63, 99-102 (2007)

Adachi W, Suzuki NN, Fujioka Y, Suzuki K, Ohsumi Y, Inagaki F.
Crystallization of Saccharomyces cerevisiae aminopeptidase 1, the major cargo protein of the Cvt pathway.
Acta Crystallograph Sect F Struct Biol Cryst Commun., 63, 200-203 (2007)

Yamaguti M, Suzuki NN, Fujioka Y, Ohsumi Y, Inagaki F.
Crystallization and preliminary X-ray analysis of Atg10.
Acta Crystallograph Sect F Struct Biol Cryst Commun., 63, 443-445 (2007)

Ushimaru T, Nakagawa T, Fujioka Y, Daicho K, Naito M, Yamauchi Y, Nonaka H, Amako K, Yamawaki K, Murata N.
Transgenic Arabidopsis plants expressing the rice dehydroascorbate reductase gene are resistant to salt stress.
J Plant Physiol., 163, 1179-1184 (2006)

Hagio Y, Kimura Y, Taira T, Fujioka Y, Iguchi-Ariga SM, Ariga H.
Distinct localizations and repression activities of MM-1 isoforms toward c-Myc.
J Cell Biochem., 97, 145-155 (2006)

Yamada Y, Suzuki NN, Fujioka Y, Ichimura Y, Ohsumi Y, Inagaki F.
Crystallization and preliminary X-ray analysis of Atg3.
Acta Crystallograph Sect F Struct Biol Cryst Commun., 62, 1016-1017 (2006)

Honbou K, Yuzawa S, Suzuki NN, Fujioka Y, Sumimoto H, Inagaki F.
Crystallization and preliminary crystallographic analysis of p40phox, a regulatory subunit of NADPH oxidase.
Acta Crystallograph Sect F Struct Biol Cryst Commun., 62, 1018-1020 (2006)

Matsushita M, Suzuki NN, Fujioka Y, Ohsumi Y, Inagaki F.
Expression, purification and crystallization of the Atg5-Atg16 complex essential for autophagy.
Acta Crystallograph Sect F Struct Biol Cryst Commun., 62, 1021-1023 (2006)

Kamada Y, Fujioka Y, Suzuki NN, Inagaki F, Wullschleger S, Loewith R, Hall MN, Ohsumi Y.
Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization.
Mol Cell Biol., 25, 7239-7248 (2005)

Sugawara K, Suzuki NN, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F.
Structural basis for the specificity and catalysis of human Atg4B responsible for mammalian autophagy.
J Biol Chem., 280, 40058-40065 (2005)

Suzuki NN, Yoshimoto K, Fujioka Y, Ohsumi Y, Inagaki F.
The crystal structure of plant ATG12 and its biological implication in autophagy.
Autophagy, 1, 119-126 (2005)

Hashida S, Yuzawa S, Suzuki NN, Fujioka Y, Takikawa T, Sumimoto H, Inagaki F, Fujii H.
Binding of FAD to cytochrome b558 is facilitated during activation of the phagocyte NADPH oxidase, leading to superoxide production.
J Biol Chem., 279, 26378-26386 (2004)

Yuzawa S, Ogura K, Horiuchi M, Suzuki NN, Fujioka Y, Kataoka M, Sumimoto H, Inagaki F.
Solution structure of the tandem Src homology 3 domains of p47phox in an autoinhibited form.
J Biol Chem., 279, 29752-29760 (2004)

Yuzawa S, Suzuki NN, Fujioka Y, Ogura K, Sumimoto H, Inagaki F.
A molecular mechanism for autoinhibition of the tandem SH3 domains of p47phox, the regulatory subunit of the phagocyte NADPH oxidase.
Genes Cells, 9, 443-456 (2004)

Yuzawa S, Yokochi M, Fujioka Y, Ogura K, Sumimoto H, Inagaki F.
Sequence-specific resonance assignments of the tandem SH3 domains in an autoinhibitory form of p47(phox).
J Biomol NMR, 29, 451-452 (2004)

Sugawara K, Suzuki NN, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F.
The crystal structure of microtubule-associated protein light chain 3, a mammalian homologue of Saccharomyces cerevisiae Atg8.
Genes Cells, 9, 611-618 (2004)

Sugawara K, Suzuki NN, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F.
Crystallization and preliminary X-ray analysis of LC3-I.
Acta Crystallogr D Biol Crystallogr., 59, 1464-1465 (2003)

Yuzawa S, Suzuki NN, Fujioka Y, Ogura K, Sumimoto H, Inagaki F.
Crystallization and preliminary crystallographic analysis of the autoinhibited form of the tandem SH3 domain of p47(phox).
Acta Crystallogr D Biol Crystallogr., 59, 1479-1480 (2003)

Fujioka Y, Taira T, Maeda Y, Tanaka S, Nishihara H, Iguchi-Ariga SM, Nagashima K, Ariga H.
MM-1, a c-Myc-binding protein, is a candidate for a tumor suppressor in leukemia/lymphoma and tongue cancer.
J Biol Chem., 276, 45137-45144 (2001)

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