北大構造生物学研究室

オートファジーの構造生物学

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Home > メンバー > 稲垣　冬彦

		稲垣　冬彦
		北海道大学大学院構造生物学研究室教授
		finagaki@pharm.hokudai.ac.jp
		理学博士
		細胞内シグナル伝達の構造生物学新規NMR構造解析技術の開発構造生物学の創薬への展開

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Noda NN, Inagaki F.
Mechanisms of Autophagy.
Annu Rev Biophys., 44, 101-122 (2015)

Mazhab-Jafari MT, Marshall CB, Smith MJ, Gasmi-Seabrook GM, Stathopulos PB, Inagaki F, Kay LE, Neel BG, Ikura M.
Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site.
Proc Natl Acad Sci U S A, 112, 6625-6630 (2015)

Enokizono Y, Kumeta H, Funami K, Horiuchi M, Sarmiento J, Yamashita K, Standley DM, Matsumoto M, Seya T, Inagaki F.
Structures and interface mapping of the TIR domain-containing adaptor molecules involved in interferon signaling.
Proc Natl Acad Sci U S A (2013)

Tamura N, Oku M, Ito M, Noda NN, Inagaki F, Sakai Y.
Atg18 phosphoregulation controls organellar dynamics by modulating its phosphoinositide-binding activity.
J Cell Biol., 202, 685-698 (2013)

Ogura K, Kobashigawa Y, Saio T, Kumeta H, Torikai S, Inagaki F.
Practical applications of hydrostatic pressure to refold proteins from inclusion bodies for NMR structural studies.
Protein Eng Des Sel. (2013)

Kumeta H, Ogura K, Nishimiya Y, Miura A, Inagaki F, Tsuda S.
NMR structure note: a defective isoform and its activity-improved variant of a type III antifreeze protein from Zoarces elongates Kner.
J Biomol NMR (2013)

Nyirenda J, Matsumoto S, Saitoh T, Maita N, Noda NN, Inagaki F, Kohda D.
Crystallographic and NMR Evidence for Flexibility in Oligosaccharyltransferases and Its Catalytic Significance.
Structure (2012)

Noda NN, Fujioka Y, Hanada T, Ohsumi Y, Inagaki F.
Structure of the Atg12-Atg5 conjugate reveals a platform for stimulating Atg8-PE conjugation.
EMBO Rep. (2012)

Yamaguchi M, Matoba K, Sawada R, Fujioka Y, Nakatogawa H, Yamamoto H, Kobashigawa Y, Hoshida H, Akada R, Ohsumi Y, Noda NN, Inagaki F.
Noncanonical recognition and UBL loading of distinct E2s by autophagy-essential Atg7.
Nat Struct Mol Biol., 19, 1250-1256 (2012)

Yokogawa M, Kobashigawa Y, Yoshida N, Ogura K, Harada K, Inagaki F.
NMR analyses of the interaction between the EEA1 FYVE domain and phosphoinositide embedded in lipid bilayer.
J Biol Chem., 287, 34936-34945 (2012)

Horiuchi M, Takahasi K, Kobashigawa Y, Ochiai M, Inagaki F.
A low-cost affinity purification system using β-1,3-glucan recognition protein and curdlan beads.
Protein Eng Des Sel., 25, 405-413 (2012)

Hayashi T, Senda M, Morohashi H, Higashi H, Horio M, Kashiba Y, Nagase L, Sasaya D, Shimizu T, Venugopalan N, Kumeta H, Noda NN, Inagaki F, Senda T, Hatakeyama M.
Tertiary Structure-Function Analysis Reveals the Pathogenic Signaling Potentiation Mechanism of Helicobacter pylori Oncogenic Effector CagA.
Cell Host Microbe., 12, 20-33 (2012)

Ogura K, Okamura H, Katahira M, Katoh E, Inagaki F.
Conformational dynamics of yeast calmodulin in the Ca(2+)-bound state probed using NMR relaxation dispersion.
FEBS Lett., 586, 2548-2554 (2012)

Yamaguchi M, Noda NN, Yamamoto H, Shima T, Kumeta H, Kobashigawa Y, Akada R, Ohsumi Y, Inagaki F.
Structural Insights into Atg10-Mediated Formation of the Autophagy-Essential Atg12-Atg5 Conjugate.
Structure, 20, 1244-1254 (2012)

Kobashigawa Y, Inagaki F.
Structural biology: CrkL is not Crk-like.
Nat Chem Biol., 8, 504-505 (2012)

Kobashigawa Y, Saio T, Ushio M, Sekiguchi M, Yokochi M, Ogura K, Inagaki F.
Convenient method for resolving degeneracies due to symmetry of the magnetic susceptibility tensor and its application to pseudo contact shift-based protein-protein complex structure determination.
J Biomol NMR, 53, 53-63 (2012)

Noda NN, Kobayashi T, Adachi W, Fujioka Y, Ohsumi Y, Inagaki F.
Structure of the Novel C-terminal Domain of Vacuolar Protein Sorting 30/Autophagy-related Protein 6 and Its Specific Role in Autophagy.
J Biol Chem., 287, 16256-16266 (2012)

Kondo-Okamoto N, Noda NN, Suzuki SW, Nakatogawa H, Takahashi I, Matsunami M, Hashimoto A, Inagaki F, Ohsumi Y, Okamoto K.
Autophagy-related Protein 32 Acts as Autophagic Degron and Directly Initiates Mitophagy.
J Biol Chem., 287, 10631-10638 (2012)

Ogura K, Kumeta H, Takahasi K, Kobashigawa Y, Yoshida R, Itoh H, Yazawa M, Inagaki F.
Solution structures of yeast Saccharomyces cerevisiae calmodulin in calcium- and target peptide-bound states reveal similarities and differences to vertebrate calmodulin.
Genes Cells, 17, 159-172 (2012)

Kobashigawa Y, Tomitaka A, Kumeta H, Noda NN, Yamaguchi M, Inagaki F
Autoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-b.
Proc Natl Acad Sci U S A, 108, 20579-20584 (2011)

Noda NN, Satoo K, Fujioka Y, Kumeta H, Ogura K, Nakatogawa H, Ohsumi Y, Inagaki F.
Structural basis of Atg8 activation by a homodimeric E1, Atg7.
Mol Cell, 44, 462-475 (2011)

Kobashigawa Y, Harada K, Yoshida N, Ogura K, Inagaki F.
Phosphoinositide-incorporated lipid-protein nanodiscs: A tool for studying protein-lipid interactions.
Anal Biochem, 410, 77-83 (2011)

Ogura K, Kumeta H, Inagaki F.
Structure determination of proteins in (2)H (2)O solution aided by a deuterium-decoupled 3D HCA(N)CO experiment.
J Biomol NMR (2010)

Takaku T, Ogura K, Kumeta H, Yoshida N, Inagaki F.
Solution structure of a novel Cdc42-binding module of Bem1 and its interaction with Ste20 and Cdc42.
J Biol Chem., 285, 19346-19353 (2010)

Takahasi K, Ochiai M, Horiuchi M, Kumeta H, Ogura K, Ashida M, Inagaki F.
Solution structure of the silkworm betaGRP/GNBP3 N-terminal domain reveals the mechanism for beta-1,3-glucan-specific recognition.
Proc Natl Acad Sci U S A, 106, 11679-11684 (2009)

Saio T, Yokochi M, Inagaki F.
The NMR structure of the p62 PB1 domain, a key protein in autophagy and NF-kappaB signaling pathway.
J Biomol NMR (2009)

Horiuchi M, Takeuchi K, Noda N, Muroya N, Suzuki T, Nakamura T, Kawamura-Tsuzuku J, Takahasi K, Yamamoto T, Inagaki F.
Structural basis for the antiproliferative activity of the Tob-hCaf1 complex.
J Biol Chem., 284, 13244-13255 (2009)

Takahasi K, Kumeta H, Tsuduki N, Narita R, Shigemoto T, Hirai R, Yoneyama M, Horiuchi M, Ogura K, Fujita T, Inagaki F.
Solution structures of cytosolic RNA sensors MDA5 and LGP2 C-terminal domains: Identification of the RNA recognition loop in RIG-I like receptors.
J Biol Chem., 284, 17465-17474 (2009)

Ogura K, Tandai T, Yoshinaga S, Kobashigawa Y, Kumeta H, Ito T, Sumimoto H, Inagaki F.
NMR structure of the heterodimer of Bem1 and Cdc24 PB1 domains from Saccharomyces cerevisiae.
J Biochem (Tokyo), 146, 317-325 (2009)

Satoo K, Noda NN, Kumeta H, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F.
The structure of Atg4B-LC3 complex reveals the mechanism of LC3-processing and delipidation during autophagy
EMBO J., 28, 1341-1350 (2009)

Noda, N.N., Ohsumi, Y., Inagaki, F.
Atg systems from the protein structural point of view
Chem. Rev., 109, 1587-1598 (2009)

Watanabe Y, Noda NN, Honbou K, Suzuki K, Sakai Y, Ohsumi Y, Inagaki F
Crystallization of Saccharomyces cerevisiae alpha-mannosidase, a cargo protein of the Cvt pathway
Acta Crystallogr Sect F Struct Biol Cryst Commun., 65, 571-573 (2009)

Saio T, Ogura K, Yokochi M, Kobashigawa Y, Inagaki F.
Two-point anchoring of a lanthanide-binding peptide to a target protein enhances the paramagnetic anisotropic effect.
J Biomol NMR, 44, 157-166 (2009)

Kobashigawa Y, Kumeta H, Kanoh D, Inagaki F
The NMR structure of the TC10- and Cdc42-interacting domain of CIP4
J Biomol NMR, 44, 113-118 (2009)

Kobashigawa Y, Kumeta H, Ogura K, Inagaki F
Attachment of an NMR-invisible solubility enhancement tag using a sortase-mediated protein ligation method.
J Biomol NMR, 43, 145-150 (2009)

Noda NN, Kumeta H, Nakatogawa H, Satoo K, Adachi W, Ishii J, Fujioka Y, Ohsumi Y, Inagaki F.
Structural basis of target recognition by Atg8/LC3 during selective autophagy.
Genes Cells, 13, 1211-1218 (2008)

Fujioka Y, Noda NN, Matsushita M, Ohsumi Y, Inagaki F
Crystallization of the coiled-coil domain of Atg16 essential for autophagy
Acta Crystallogr Sect F Struct Biol Cryst Commun., 64, 1046-1048 (2008)

Takahasi K, Yoneyama M, Nishihori T, Hirai R, Kumeta H, Narita R, Gale M Jr, Inagaki F, Fujita T.
Nonself RNA-Sensing Mechanism of RIG-I Helicase and Activation of Antiviral Immune Responses.
Mol Cell, 29, 428-440 (2008)

Fujioka Y, Noda NN, Fujii K, Yoshimoto K, Ohsumi Y, Inagaki F.
In vitro reconstitution of plant ATG8 and ATG12 conjugation systems essential for autophagy
J Biol Chem., 283, 1921-1928 (2008)

Noda NN, Fujioka Y, Ohsumi Y, Inagaki F.
Crystallization of the Atg12-Atg5 conjugate bound to Atg16 by the free interface diffusion method.
J Synchrotron Radiat., 15, 266-268 (2008)

Kumeta H, Ogura K, Adachi S, Fujioka Y, Tanuma N, Kikuchi K, Inagaki F.
The NMR structure of the NIPP1 FHA domain.
J Biomol NMR, 40, 219-224 (2008)

Hanada T, Noda NN, Satomi Y, Ichimura Y, Fujioka Y, Takao T, Inagaki F, Ohsumi Y.
The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy.
J Biol Chem., 282, 37298-37302 (2007)

Kumeta H, Ogura K, Asayama M, Katoh S, Katoh E, Teshima K, Inagaki F.
The NMR structure of the domain II of a chloroplastic NifU-like protein OsNifU1A.
J Biomol NMR, 38, 161-164 (2007)

Saio T, Kumeta H, Ogura K, Yokochi M, Asayama M, Katoh S, Katoh E, Teshima K, Inagaki F.
The Cooperative Role of OsCnfU-1A Domain I and Domain II in the Iron Sulphur Cluster Transfer Process as Revealed by NMR.
J Biochem (Tokyo), 142, 113-121 (2007)

Yamaguti M, Suzuki NN, Fujioka Y, Ohsumi Y, Inagaki F.
Crystallization and preliminary X-ray analysis of Atg10.
Acta Crystallogr Sect F Struct Biol Cryst Commun., 63, 443-445 (2007)

Adachi W, Suzuki NN, Fujioka Y, Suzuki K, Ohsumi Y, Inagaki F.
Crystallization of Saccharomyces cerevisiae aminopeptidase 1, the major cargo protein of the Cvt pathway.
Acta Crystallogr Sect F Struct Biol Cryst Commun., 63, 200-203 (2007)

Honbou K, Minakami R, Yuzawa S, Takeya R, Suzuki NN, Kamakura S, Sumimoto H, Inagaki F.
Full-length p40phox structure suggests a basis for regulation mechanism of its membrane binding.
EMBO J., 26, 1176-1186 (2007)

Satoo K, Suzuki NN, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F.
Crystallization and preliminary crystallographic analysis of human Atg4B-LC3 complex.
Acta Crystallogr Sect F Struct Biol Cryst Commun., 63, 99-102 (2007)

Yamada Y, Suzuki NN, Hanada T, Ichimura Y, Kumeta H, Fujioka Y, Ohsumi Y, Inagaki F.
The crystal structure of Atg3, an autophagy-related ubiquitin carrier protein (E2) enzyme that mediates Atg8 lipidation.
J Biol Chem., 282, 8036-8043 (2007)

Matsushita M, Suzuki NN, Obara K, Fujioka Y, Ohsumi Y, Inagaki F.
Structure of Atg5.Atg16, a complex essential for autophagy.
J Biol Chem., 282, 6763-6772 (2007)

Kobashigawa Y, Sakai M, Naito M, Yokochi M, Kumeta H, Makino Y, Ogura K, Tanaka S, Inagaki F.
Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK.
Nat Struct Mol Biol., 14, 503-510 (2007)

Kobashigawa Y, Naito M, Inagaki F.
An efficient method for protein phosphorylation using the artificially introduction of cognate binding modules into kinases and substrates.
J Biotechnol., 131, 458-465 (2007)

Uemura S, Kurose T, Suzuki T, Yoshida S, Ito M, Saito M, Horiuchi M, Inagaki F, Igarashi Y, Inokuchi J.
Substitution of the N-glycan function in glycosyltransferases by specific amino acids: ST3Gal-V as a model enzyme.
Glycobiology., 16, 258-270 (2006)

Ogura K, Nobuhisa I, Yuzawa S, Takeya R, Torikai S, Saikawa K, Sumimoto H, Inagaki F.
NMR solution structure of the tandem Src homology 3 domains of p47phox complexed with a p22phox-derived proline-rich peptide.
J Biol Chem., 281, 3660-3668 (2006)

Nobuhisa I, Takeya R, Ogura K, Ueno N, Kohda D, Inagaki F, Sumimoto H.
Activation of the superoxide-producing phagocyte NADPH oxidase requires co-operation between the tandem SH3 domains of p47phox in recognition of a polyproline type II helix and an adjacent alpha-helix of p22phox.
Biochem J., 396, 183-192 (2006)

Matsushita M, Suzuki NN, Fujioka Y, Ohsumi Y, Inagaki F.
Expression, purification and crystallization of the Atg5-Atg16 complex essential for autophagy.
Acta Crystallogr Sect F Struct Biol Cryst Commun., 62, 1021-1023 (2006)

Honbou K, Yuzawa S, Suzuki NN, Fujioka Y, Sumimoto H, Inagaki F.
Crystallization and preliminary crystallographic analysis of p40phox, a regulatory subunit of NADPH oxidase.
Acta Crystallogr Sect F Struct Biol Cryst Commun., 62, 1018-1020 (2006)

Yamada Y, Suzuki NN, Fujioka Y, Ichimura Y, Ohsumi Y, Inagaki F.
Crystallization and preliminary X-ray analysis of Atg3.
Acta Crystallogr Sect F Struct Biol Cryst Commun., 62, 1016-1017 (2006)

Watanabe Y, Inanami O, Horiuchi M, Hiraoka W, Shimoyama Y, Inagaki F, Kuwabara M.
Identification of pH-sensitive regions in the mouse prion by the cysteine-scanning spin-labeling ESR technique.
Biochem Biophys Res Commun., 350, 549-556 (2006)

Hirano Y, Yoshinaga S, Takeya R, Suzuki NN, Horiuchi M, Kohjima M, Sumimoto H, Inagaki F.
Structure of a cell polarity regulator, a complex between atypical PKC and Par6 PB1 domains.
J Biol Chem., 280, 9653-9661 (2005)

Ichikawa S, Takai T, Inoue T, Yuuki T, Okumura Y, Ogura K, Inagaki F, Hatanaka H.
NMR study on the major mite allergen Der f 2: its refined tertiary structure, epitopes for monoclonal antibodies and characteristics shared by ML protein group members.
J Biochem (Tokyo), 137, 255-263 (2005)

Yoshida S, Ogura K, Yokochi M, Yuzawa S, Horiuchi M, Morioka H, Sumimoto H, Inagaki F.
1H, 13C and 15N resonance assignments of the backbone and methyl groups of the 24 kDa tetratricopeptide repeat domain in p67(phox).
J Biomol NMR, 32, 176 (2005)

Kamada Y, Fujioka Y, Suzuki NN, Inagaki F, Wullschleger S, Loewith R, Hall MN, Ohsumi Y.
Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization.
Mol Cell Biol., 25, 7239-7248 (2005)

Suzuki NN, Yoshimoto K, Fujioka Y, Ohsumi Y, Inagaki F.
The crystal structure of plant ATG12 and its biological implication in autophagy.
Autophagy., 1, 119-126 (2005)

Inanami O, Hashida S, Iizuka D, Horiuchi M, Hiraoka W, Shimoyama Y, Nakamura H, Inagaki F, Kuwabara M.
Conformational change in full-length mouse prion: a site-directed spin-labeling study.
Biochem Biophys Res Commun., 335, 785-792 (2005)

Sugawara K, Suzuki NN, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F.
Structural basis for the specificity and catalysis of human Atg4B responsible for mammalian autophagy.
J Biol Chem., 280, 40058-40065 (2005)

Katoh S, Murata K, Kubota Y, Kumeta H, Ogura K, Inagaki F, Asayama M, Katoh E.
Refolding and purification of recombinant OsNifU1A domain II that was expressed by Escherichia coli.
Protein Expr Purif., 43, 149-156 (2005)

Mori M, Yoneyama M, Ito T, Takahashi K, Inagaki F, Fujita T.
Identification of Ser-386 of interferon regulatory factor 3 as critical target for inducible phosphorylation that determines activation.
J Biol Chem., 279, 9698-9702 (2004)

Suzuki NN, Koizumi K, Fukushima M, Matsuda A, Inagaki F.
Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase.
Structure, 12, 751-764 (2004)

Yuzawa S, Suzuki NN, Fujioka Y, Ogura K, Sumimoto H, Inagaki F.
A molecular mechanism for autoinhibition of the tandem SH3 domains of p47phox, the regulatory subunit of the phagocyte NADPH oxidase.
Genes Cells, 9, 443-456 (2004)

Hashida S, Yuzawa S, Suzuki NN, Fujioka Y, Takikawa T, Sumimoto H, Inagaki F, Fujii H.
Binding of FAD to cytochrome b558 is facilitated during activation of the phagocyte NADPH oxidase, leading to superoxide production.
J Biol Chem., 279, 26378-26386 (2004)

Yuzawa S, Yokochi M, Fujioka Y, Ogura K, Sumimoto H, Inagaki F.
Sequence-specific resonance assignments of the tandem SH3 domains in an autoinhibitory form of p47(phox).
J Biomol NMR, 29, 451-452 (2004)

Yuzawa S, Ogura K, Horiuchi M, Suzuki NN, Fujioka Y, Kataoka M, Sumimoto H, Inagaki F.
Solution structure of the tandem Src homology 3 domains of p47phox in an autoinhibited form.
J Biol Chem., 279, 29752-29760 (2004)

Sugawara K, Suzuki NN, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F.
The crystal structure of microtubule-associated protein light chain 3, a mammalian homologue of Saccharomyces cerevisiae Atg8.
Genes Cells, 9, 611-618 (2004)

Hirano Y, Yoshinaga S, Ogura K, Yokochi M, Noda Y, Sumimoto H, Inagaki F.
Solution structure of atypical protein kinase C PB1 domain and its mode of interaction with ZIP/p62 and MEK5.
J Biol Chem., 279, 31883-31890 (2004)

Honbou K, Suzuki NN, Horiuchi M, Taira T, Niki T, Ariga H, Inagaki F.
Crystallization and preliminary crystallographic analysis of DJ-1, a protein associated with male fertility and parkinsonism.
Acta Crystallogr D Biol Crystallogr., 59, 1502-1503 (2003)

Yuzawa S, Suzuki NN, Fujioka Y, Ogura K, Sumimoto H, Inagaki F.
Crystallization and preliminary crystallographic analysis of the autoinhibited form of the tandem SH3 domain of p47(phox).
Acta Crystallogr D Biol Crystallogr., 59, 1479-1480 (2003)

Suzuki NN, Koizumi K, Fukushima M, Matsuda A, Inagaki F.
Crystallization and preliminary X-ray analysis of human uridine-cytidine kinase 2.
Acta Crystallogr D Biol Crystallogr., 59, 1477-1478 (2003)

Honbou K, Suzuki NN, Horiuchi M, Niki T, Taira T, Ariga H, Inagaki F.
The crystal structure of DJ-1, a protein related to male fertility and Parkinson's disease.
J Biol Chem., 278, 31380-31384 (2003)

Sugawara K, Suzuki NN, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F.
Crystallization and preliminary X-ray analysis of LC3-I.
Acta Crystallogr D Biol Crystallogr., 59, 1464-1465 (2003)

Yuzawa S, Ogura K, Hatanaka H, Miura K, Inagaki F.
Backbone assignments of Grb2 complexed with ligand peptides for SH3 and SH2 domains.
J Biomol NMR, 27, 185-186 (2003)

Yoshinaga S, Kohjima M, Ogura K, Yokochi M, Takeya R, Ito T, Sumimoto H, Inagaki F.
The PB1 domain and the PC motif-containing region are structurally similar protein binding modules.
EMBO J., 22, 4888-4897 (2003)

Noda Y, Kohjima M, Izaki T, Ota K, Yoshinaga S, Inagaki F, Ito T, Sumimoto H.
Molecular recognition in dimerization between PB1 domains.
J Biol Chem., 278, 43516-43524 (2003)

Takahasi K, Suzuki NN, Horiuchi M, Mori M, Suhara W, Okabe Y, Fukuhara Y, Terasawa H, Akira S, Fujita T, Inagaki F.
X-ray crystal structure of IRF-3 and its functional implications.
Nat Struct Biol., 10, 922-927 (2003)

Ponting CP, Ito T, Moscat J, Diaz-Meco MT, Inagaki F, Sumimoto H.
OPR, PC and AID: all in the PB1 family.
Trends Biochem Sci., 27, 10 (2002)

Ogura K, Nagata K, Horiuchi M, Ebisui E, Hasuda T, Yuzawa S, Nishida M, Hatanaka H, Inagaki F.
Solution structure of N-terminal SH3 domain of Vav and the recognition site for Grb2 C-terminal SH3 domain.
J Biomol NMR, 22, 37-46 (2002)

Takai T, Hatanaka H, Ichikawa S, Yokota T, Inagaki F, Okumura Y.
Effects of double mutation at two distant IgE-binding sites in the three-dimensional structure of the major house dust mite allergen Der f 2 on IgE-binding and histamine-releasing activity.
Biosci Biotechnol Biochem., 65, 1601-1609 (2001)

Terasawa H, Noda Y, Ito T, Hatanaka H, Ichikawa S, Ogura K, Sumimoto H, Inagaki F.
Structure and ligand recognition of the PB1 domain: a novel protein module binding to the PC motif.
EMBO J., 20, 3947-3956 (2001)

Nishida M, Nagata K, Hachimori Y, Horiuchi M, Ogura K, Mandiyan V, Schlessinger J, Inagaki F.
Novel recognition mode between Vav and Grb2 SH3 domains.
EMBO J., 20, 2995-3007 (2001)

Kawasaki M, Inagaki F.
Random PCR-based screening for soluble domains using green fluorescent protein.
Biochem Biophys Res Commun., 280, 842-844 (2001)

Yuzawa S, Yokochi M, Hatanaka H, Ogura K, Kataoka M, Miura K, Mandiyan V, Schlessinger J, Inagaki F.
Solution structure of Grb2 reveals extensive flexibility necessary for target recognition.
J Mol Biol., 306, 527-537 (2001)

Kawakami T, Hasegawa K, Teruya K, Akaji K, Horiuchi M, Inagaki F, Kurihara Y, Uesugi S, Aimoto S.
Polypeptide synthesis using an expressed peptide as a building block for condensation with a peptide thioester: application to the synthesis of phosphorylated p21Max protein(1-101).
J Pept Sci., 7, 474-487 (2001)

Takai T, Ichikawa S, Hatanaka H, Inagaki F, Okumura Y.
Effects of proline mutations in the major house dust mite allergen Der f 2 on IgE-binding and histamine-releasing activity.
Eur J Biochem., 267, 6650-6656 (2000)

Takai T, Ichikawa S, Yokota T, Hatanaka H, Inagaki F, Okumura Y.
Unlocking the allergenic structure of the major house dust mite allergen der f 2 by elimination of key intramolecular interactions.
FEBS Lett., 484, 102-107 (2000)

Kawakami T, Hasegawa K, Teruya K, Akaji K, Horiuchi M, Inagaki F, Kurihara Y, Uesugi S, Aimoto S.
Polypeptide Synthesis Using an Expressed Peptide as a Building Block via the Thioester Method.
Tetrahedron Letters., 41, 2625-2628 (2000)

Sugita M, Miwa S, Aoki K, Dulaney JT, Ichikawa S, Inagaki F, Suzuki M.
Acidic Glycosphingolipids in Brackish Water Annelida: Structural Analysis of Two Novel Glycoinositolphospholipids from the Lugworm, Tylorrhynchus heterochetus.
J Jpn Oil Chem Soc., 49, 33-43 (2000)

Kawakami T, Hasegawa K, Teruya K, Akaji K, Horiuchi M, Inagaki F, Kurihara Y, Uesugi S, Aimoto S.
Use of an Expressed Peptide Segment as a Building Block for the Preparation of Phosphorylated Polypeptide via the Thioester Method.
J Pept Sci., 111-112 (1999)

Nishiyama C, Hatanaka H, Ichikawa S, Fukada M, Akagawa-Chihara M, Yuuki T, Yokota T, Inagaki F, Okumura Y.
Analysis of human IgE epitope of Der f 2 with anti-Der f 2 mouse monoclonal antibodies.
Mol Immunol., 36, 53-60 (1999)

Koga H, Terasawa H, Nunoi H, Takeshige K, Inagaki F, Sumimoto H.
Tetratricopeptide repeat (TPR) motifs of p67(phox) participate in interaction with the small GTPase Rac and activation of the phagocyte NADPH oxidase.
J Biol Chem., 274, 25051-25060 (1999)

Ogura K, Tsuchiya S, Terasawa H, Yuzawa S, Hatanaka H, Mandiyan V, Schlessinger J, Inagaki F.
Solution structure of the SH2 domain of Grb2 complexed with the Shc-derived phosphotyrosine-containing peptide.
J Mol Biol., 289, 439-445 (1999)

Tsuchiya S, Ogura K, Hatanaka H, Nagata K, Terasawa H, Mandiyan V, Schlessinger J, Aimoto S, Ohta H, Inagaki F.
Solution structure of the SH2 domain of Grb2/Ash complexed with EGF receptor-derived phosphotyrosine-containing peptide.
J Biochem (Tokyo), 125, 1151-1159 (1999)

Ogura K, Nagata K, Hatanaka H, Habuchi H, Kimata K, Tate S, Ravera MW, Jaye M, Schlessinger J, Inagaki F.
Solution structure of human acidic fibroblast growth factor and interaction with heparin-derived hexasaccharide.
J Biomol NMR, 13, 11-24 (1999)

Akhter S, Ichihara-Tanaka K, Kojima S, Muramatsu H, Inui T, Kimura T, Kaneda N, Talukder AH, Kadomatsu K, Inagaki F, Muramatsu T.
Clusters of basic amino acids in midkine: roles in neurite-promoting activity and plasminogen activator-enhancing activity.
J Biochem (Tokyo), 123, 1127-1136 (1998)

Abe Y, Odaka M, Inagaki F, Lax I, Schlessinger J, Kohda D.
Disulfide bond structure of human epidermal growth factor receptor.
J Biol Chem., 273, 11150-11157 (1998)

Ichikawa S, Hatanaka H, Yuuki T, Iwamoto N, Kojima S, Nishiyama C, Ogura K, Okumura Y, Inagaki F.
Solution structure of Der f 2, the major mite allergen for atopic diseases.
J Biol Chem., 273, 356-360 (1998)

Mizoguchi T, Sakamoto S, Koyama Y, Ogura K, Inagaki F.
The structure of the Aggregate Form of Bacteriochlorophyll c Showing the Qy Absorption above 740 nm as Determined by the Ring-current Effects on 1H and 13C Nuclei and by 1H-1H Intermolecular NOE Correlations.
Photochemistry and Photobiology., 67, 239-248 (1998)

Ogura K, Tsuchiya S, Terasawa H, Yuzawa S, Hatanaka H, Mandiyan V, Schlessinger J, Inagaki F.
Conformation of an Shc-derived phosphotyrosine-containing peptide complexed with the Grb2 SH2 domain.
J Biomol NMR, 10, 273-278 (1997)

Asai T, Watanabe K, Ichihara-Tanaka K, Kaneda N, Kojima S, Iguchi A, Inagaki F, Muramatsu T.
Identification of heparin-binding sites in midkine and their role in neurite-promotion.
Biochem Biophys Res Commun., 236, 66-70 (1997)

Iwasaki W, Nagata K, Hatanaka H, Inui T, Kimura T, Muramatsu T, Yoshida K, Tasumi M, Inagaki F.
Solution structure of midkine, a new heparin-binding growth factor.
EMBO J., 16, 6936-6946 (1997)

Hatanaka H, Tanimura R, Katoh S, Inagaki F.
Solution structure of ferredoxin from the thermophilic cyanobacterium Synechococcus elongatus and its thermostability.
J Mol Biol., 268, 922-933 (1997)

Odaka M, Kohda D, Lax I, Schlessinger J, Inagaki F.
Ligand-binding enhances the affinity of dimerization of the extracellular domain of the epidermal growth factor receptor.
J Biochem (Tokyo), 122, 116-121 (1997)

Ogura K, Terasawa H, Inagaki F.
An Improved Double-tuned and Isotope-Filtered Pulse Shceme Based on a Pulsed Field Gradient and a Wide-Band Inversion Shaped Pulse.
J Biomol NMR, 8, 492-498 (1996)

Kohda D, Morton CJ, Parkar AA, Hatanaka H, Inagaki FM, Campbell ID, Day AJ.
Solution structure of the link module: a hyaluronan-binding domain involved in extracellular matrix stability and cell migration.
Cell., 86, 767-775 (1996)

Hatanaka H, Ogura K, Moriyama K, Ichikawa S, Yahara I, Inagaki F.
Tertiary structure of destrin and structural similarity between two actin-regulating protein families.
Cell., 85, 1047-1055 (1996)

Ogura K, Terasawa H, Inagaki F.
Fully 13C-Refocused Multidimensional 13C-Edited Pulse Schemes Using Broadband Shaped Inversion and Refocusing Pulses.
J Magn Reson B. , 112, 63-68 (1996)

Shibuya K, Kaji H, Itoh T, Ohyama Y, Tsujikami A, Tate S, Takeda A, Kumagai I, Hirao I, Miura K, Inagaki F.
Human cystatin A is inactivated by engineered truncation. The NH2-terminal region of the cysteine proteinase inhibitor is essential for expression of its inhibitory activity.
Biochemistry., 34, 12185-12192 (1995)

Tate S, Ushioda T, Utsunomiya-Tate N, Shibuya K, Ohyama Y, Nakano Y, Kaji H, Inagaki F, Samejima T, Kainosho M.
Solution structure of a human cystatin A variant, cystatin A2-98 M65L, by NMR spectroscopy. A possible role of the interactions between the N- and C-termini to maintain the inhibitory active form of cystatin A.
Biochemistry., 34, 14637-14648 (1995)

Shibuya K, Kaji H, Ohyama Y, Tate S, Kainosho M, Inagaki F, Samejima T.
Significance of the highly conserved Gly-4 residue in human cystatin A.
J Biochem (Tokyo), 118, 635-642 (1995)

Sugita M, Fujii H, Dulaney JT, Inagaki F, Suzuki M, Suzuki A, Ohta S.
Structural elucidation of two novel amphoteric glycosphingolipids from the earthworm, Pheretima hilgendorfi.
Biochim Biophys Acta., 1259, 220-226 (1995)

Fujiwaki T, Hamanaka S, Tate S, Inagaki F, Suzuki M, Suzuki A, Mori C.
Tissue accumulation of sulfatide and GM3 ganglioside in a patient with variant Farber disease.
Clin Chim Acta., 234, 23-36 (1995)

Nagata K, Hatanaka H, Kohda D, Kataoka H, Nagasawa H, Isogai A, Ishizaki H, Suzuki A, Inagaki F.
Identification of the receptor-recognition surface of bombyxin-II, an insulin-like peptide of the silkmoth Bombyx mori: critical importance of the B-chain central part.
J Mol Biol., 253, 759-770 (1995)

Nagata K, Hatanaka H, Kohda D, Kataoka H, Nagasawa H, Isogai A, Ishizaki H, Suzuki A, Inagaki F.
Three-dimensional solution structure of bombyxin-II an insulin-like peptide of the silkmoth Bombyx mori: structural comparison with insulin and relaxin.
J Mol Biol., 253, 749-758 (1995)

Hashimoto R, Fujiwara H, Higashihashi N, Enjoh-Kimura T, Terasawa H, Fujita-Yamaguchi Y, Inagaki F, Perdue JF, Sakano K.
N-terminal deletion mutants of insulin-like growth factor-II (IGF-II) show Thr7 and Leu8 important for binding to insulin and IGF-I receptors and Leu8 critical for all IGF-II functions.
J Biol Chem., 270, 18013-18018 (1995)

Kohda D, Inagaki F.
Trajectory analysis of NMR structure calculations.
J Biomol NMR, 5, 357-361 (1995)

Ichikawa S, Hatanaka H, Takeuchi Y, Ohno S, Inagaki F.
Solution structure of cysteine-rich domain of protein kinase C alpha.
J Biochem (Tokyo), 117, 566-574 (1995)

Terasawa H, Kohda D, Hatanaka H, Tsuchiya S, Ogura K, Nagata K, Ishii S, Mandiyan V, Ullrich A, Schlessinger J, Inagaki F.
Structure of the N-terminal SH3 domain of GRB2 complexed with a peptide from the guanine nucleotide releasing factor Sos.
Nat Struct Biol., 1, 891-897 (1994)

Hidari KI, Kawashima I, Tai T, Inagaki F, Nagai Y, Sanai Y.
In vitro synthesis of disialoganglioside (GD1 alpha) from asialo-GM1 using sialyltransferases in rat liver Golgi vesicles.
Eur J Biochem., 221, 603-609 (1994)

Sekine M, Hashimoto Y, Suzuki M, Inagaki F, Takio K, Suzuki A.
Purification and characterization of UDP-GlcNAc:IV3 beta Gal-Gb4Cer beta-1,6-GlcNAc transferase from mouse kidney.
J Biol Chem., 269, 31143-31148 (1994)

Hamanaka Y, Hamanaka S, Shinagawa Y, Suzuki T, Inagaki F, Suzuki M, Suzuki A.
Ganglioside antigen of DU-PAN-2 in a human pancreatic cancer.
FEBS Lett., 353, 48-52 (1994)

Terasawa H, Kohda D, Hatanaka H, Nagata K, Higashihashi N, Fujiwara H, Sakano K, Inagaki F.
Solution structure of human insulin-like growth factor II; recognition sites for receptors and binding proteins.
EMBO J., 13, 5590-5597 (1994)

Kohda D, Terasawa H, Ichikawa S, Ogura K, Hatanaka H, Mandiyan V, Ullrich A, Schlessinger J, Inagaki F.
Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2.
Structure, 2, 1029-1040 (1994)

Nagata K, Kohda D, Hatanaka H, Ichikawa S, Matsuda S, Yamamoto T, Suzuki A, Inagaki F.
Solution structure of the epidermal growth factor-like domain of heregulin-alpha, a ligand for p180erbB-4.
EMBO J., 13, 3517-3523 (1994)

Hatanaka H, Oka M, Kohda D, Tate S, Suda A, Tamiya N, Inagaki F.
Tertiary structure of erabutoxin b in aqueous solution as elucidated by two-dimensional nuclear magnetic resonance.
J Mol Biol., 240, 155-166 (1994)

Yuki N, Taki T, Inagaki F, Kasama T, Takahashi M, Saito K, Handa S, Miyatake T.
A bacterium lipopolysaccharide that elicits Guillain-Barre syndrome has a GM1 ganglioside-like structure.
J Exp Med., 178, 1771-1775 (1993)

Kitagawa H, Nakada H, Fukui S, Funakoshi I, Kawasaki T, Tate S, Inagaki F, Yamashina I.
Novel gangliosides containing the sialyl-Le(a) structure from a human rectal adenocarcinoma.
J Biol Chem., 268, 26541-26545 (1993)

Kawakami Y, Nakamura K, Kojima H, Suzuki M, Inagaki F, Suzuki A, Sonoki S, Uchida A, Murata Y, Tamai Y.
A novel fucosylated glycosphingolipid with a Gal beta 1-4Glc beta 1-3Gal sequence in plerocercoids of the parasite, Spirometra erinacei.
J Biochem (Tokyo), 114, 677-683 (1993)

Kitagawa H, Nakada H, Fukui S, Funakoshi I, Kawasaki T, Yamashina I, Tate S, Inagaki F.
Novel oligosaccharides with the sialyl-Le(a) structure in human milk.
J Biochem (Tokyo), 114, 504-508 (1993)

Ikura T, Go N, Kohda D, Inagaki F, Yanagawa H, Kawabata M, Kawabata S, Iwanaga S, Noguti T, Go M.
Secondary structural features of modules M2 and M3 of barnase in solution by NMR experiment and distance geometry calculation.
Proteins., 16, 341-356 (1993)

Kohda D, Hatanaka H, Odaka M, Mandiyan V, Ullrich A, Schlessinger J, Inagaki F.
Solution structure of the SH3 domain of phospholipase C-gamma.
Cell., 72, 953-960 (1993)

Tamamura H, Kuroda M, Masuda M, Otaka A, Funakoshi S, Nakashima H, Yamamoto N, Waki M, Matsumoto A, Lancelin JM, Kohda D, Tate S, Inagaki F, Fujii N.
A comparative study of the solution structures of tachyplesin I and a novel anti-HIV synthetic peptide, T22 ([Tyr5,12, Lys7]-polyphemusin II), determined by nuclear magnetic resonance.
Biochim Biophys Acta., 1163, 209-216 (1993)

Kohda D, Odaka M, Lax I, Kawasaki H, Suzuki K, Ullrich A, Schlessinger J, Inagaki F.
A 40-kDa epidermal growth factor/transforming growth factor alpha-binding domain produced by limited proteolysis of the extracellular domain of the epidermal growth factor receptor.
J Biol Chem., 268, 1976-1981 (1993)

Sugita M, Fujii H, Inagaki F, Suzuki M, Hayata C, Hori T.
Polar glycosphingolipids in annelida. A novel series of glycosphingolipids containing choline phosphate from the earthworm, Pheretima hilgendorf.
J Biol Chem., 267, 22595-22598 (1992)

Nohara K, Suzuki M, Inagaki F, Sano T, Kaya K.
A novel disialoganglioside in rat spleen lymphocytes.
J Biol Chem., 267, 14982-14986 (1992)

Inagaki F, Tate S, Kubo H, Hoshi M.
A novel difucosylated neutral glycosphingolipid from the eggs of the sea urchin, Hemicentrotus pulcherrimus: II. Structural determination by two-dimensional NMR.
J Biochem (Tokyo), 112, 286-289 (1992)

Kubo H, Jiang GJ, Irie A, Suzuki M, Inagaki F, Hoshi M.
A novel difucosylated neutral glycosphingolipid from the eggs of the sea urchin, Hemicentrotus pulcherrimus: I. Purification and structural determination of the glycolipid.
J Biochem (Tokyo), 112, 281-285 (1992)

Tanaka N, Nakada H, Itoh N, Mizuno Y, Takanishi M, Kawasaki T, Tate S, Inagaki F, Yamashina I.
Novel structure of the N-acetylgalactosamine containing N-glycosidic carbohydrate chain of batroxobin, a thrombin-like snake venom enzyme.
J Biochem (Tokyo), 112, 68-74 (1992)

Inagaki F.
Structural Analysis of oligosaccharide chain of Glycolipids by Two-Dimentional NMR.
Magnetic Resonance in Chemstry., 30, 125-133 (1992)

Koide H, Muto Y, Kasai H, Kohri K, Hoshi K, Takahashi S, Tsukumo K, Sasaki T, Oka T, Miyake T, Fuwa T, Kohda D, Inagaki F, Miyazawa T, Yokoyama S.
A site-directed mutagenesis study on the role of isoleucine-23 of human epidermal growth factor in the receptor binding.
Biochim Biophys Acta., 1120, 257-261 (1992)

Wakamatsu K, Kohda D, Hatanaka H, Lancelin JM, Ishida Y, Oya M, Nakamura H, Inagaki F, Sato K.
Structure-activity relationships of mu-conotoxin GIIIA: structure determination of active and inactive sodium channel blocker peptides by NMR and simulated annealing calculations.
Biochemistry., 31, 12577-12584 (1992)

Kohda D, Inagaki F.
Three-dimensional nuclear magnetic resonance structures of mouse epidermal growth factor in acidic and physiological pH solutions.
Biochemistry., 31, 11928-11939 (1992)

Tate S, Kikumoto Y, Ichikawa S, Kaneko M, Masui Y, Kamogashira T, Ouchi M, Takahashi S, Inagaki F.
Stable isotope aided nuclear magnetic resonance study to investigate the receptor-binding site of human interleukin 1 beta.
Biochemistry., 31, 2435-2442 (1992)

Kohda D, Inagaki F.
Structure of epidermal growth factor bound to perdeuterated dodecylphosphocholine micelles determined by two-dimensional NMR and simulated annealing calculations.
Biochemistry., 31, 677-685 (1992)

Tate S, Inagaki F.
Reduction of the Water Hump Using a Composite Refocusing Pulse.
J Magn Reson., 96, 635-643 (1992)

Tate S, Tate NU, Ravera MW, Jaye M, Inagaki F.
A novel 15N-labeling method to selectively observe 15NH2 resonances of proteins in 1H-detected heteronuclear correlation spectroscopy.
FEBS Lett., 297, 39-42 (1992)

Ando S, Hirabayashi Y, Kon K, Inagaki F, Tate S, Whittaker VP.
A trisialoganglioside containing a sialyl alpha 2-6 N-acetylgalactosamine residue is a cholinergic-specific antigen, Chol-1 alpha.
J Biochem (Tokyo), 111, 287-290 (1992)

Kitagawa H, Takaoka M, Nakada H, Fukui S, Funakoshi I, Kawasaki T, Tate S, Inagaki F, Yamashina I.
Isolation and structural studies of human milk oligosaccharides that are reactive with a monoclonal antibody MSW 113.
J Biochem (Tokyo), 110, 598-604 (1991)

Kohda D, Inagaki F.
3D Structure of EGF and TGFα　Determned by NMR.
Analytical Chemistry., 7, 853-856 (1991)

Nohara K, Suzuki M, Inagaki F, Kaya K.
A GM1b-derived disialoganglioside GD1c is the predominant ganglioside of rat thymocytes.
J Biochem (Tokyo), 110, 274-278 (1991)

Itonori S, Nishizawa M, Suzuki M, Inagaki F, Hori T, Sugita M.
Polar glycosphingolipids in insect: chemical structures of glycosphingolipid series containing 2'-aminoethylphosphoryl-(----6)-N-acetylglucosamine as a polar group from larvae of the green-bottle fly, Lucilia caesar.
J Biochem (Tokyo), 110, 479-485 (1991)

Nakamura K, Suzuki M, Taya C, Inagaki F, Yamakawa T, Suzuki A.
A sialidase-susceptible ganglioside, IV3 alpha(NeuGc alpha 2-8NeuGc)-Gg4Cer, is a major disialoganglioside in WHT/Ht mouse thymoma and thymocytes.
J Biochem (Tokyo), 110, 832-841 (1991)

Tate S, Masui Y, Inagaki F.
Application of the DEPT Sequences to the Separation of 15NH and 15NH2 Resonances in 1H-detected 15N Single-Quqntum Coherence Spectroscopy; DEPT-SQC.
J Magn Reson., 94, 625-630 (1991)

Tate S, Masui Y, Inagaki F.
Spin-lock Pulses for Purging and Shaping the Water Resonances in 1H Detected 15N single Quantum Coherence Spectroscopy.
J Magn Reson., 94, 394-400 (1991)

Sato K, Ishida Y, Wakamatsu K, Kato R, Honda H, Ohizumi Y, Nakamura H, Ohya M, Lancelin JM, Kohda D, Inagaki F.
Active site of mu-conotoxin GIIIA, a peptide blocker of muscle sodium channels.
J Biol Chem., 266, 16989-16991 (1991)

Lancelin JM, Kohda D, Tate S, Yanagawa Y, Abe T, Satake M, Inagaki F.
Tertiary structure of conotoxin GIIIA in aqueous solution.
Biochemistry., 30, 6908-6916 (1991)

Kohda D, Sawada T, Inagaki F.
Characterization of pH titration shifts for all the nonlabile proton resonances a protein by two-dimensional NMR: the case of mouse epidermal growth factor.
Biochemistry., 30, 4896-4900 (1991)

Kitagawa H, Nakada H, Fukui S, Funakoshi I, Kawasaki T, Yamashina I, Tate S, Inagaki F.
Novel oligosaccharides with the sialyl-Lea structure in human milk.
Biochemistry., 30, 2869-2876 (1991)

Ikura T, Go N, Inagaki F.
Refined structure of melittin bound to perdeuterated dodecylphosphocholine micelles as studied by 2D-NMR and distance geometry calculation.
Proteins., 9, 981-989 (1991)

Nohara K, Suzuki M, Inagaki F, Ito H, Kaya K.
A unique fucoganglioside with blood group B determinant in rat spleen.
J Biochem (Tokyo), 108, 684-688 (1990)

Irie A, Kubo H, Inagaki F, Hoshi M.
Ceramide dihexosides from the spermatozoa of the starfish, Asterias amurensis, consist of gentiobiosyl- cellobiosyl-, and lactosylceramide.
J Biochem (Tokyo), 108, 531-536 (1990)

Kubo H, Irie A, Inagaki F, Hoshi M.
Gangliosides from the eggs of the sea urchin, Anthocidaris crassispina.
J Biochem (Tokyo), 108, 185-192 (1990)

Sekine M, Hashimoto Y, Inagaki F, Yamakawa T, Suzuki A.
The expression of IV6 beta[Gal beta 1-4(Fuc alpha 1-3)GlcNAc]-Gb5Cer in mouse kidney is controlled by the Gsl-5 gene through regulation of UDP-GlcNAc:Gb5Cer beta 1-6N-acetylglucosaminyltransferase activity.
J Biochem (Tokyo), 108, 103-108 (1990)

Sugita M, Inagaki F, Naito H, Hori T.
Studies on glycosphingolipids in larvae of the green-bottle fly, Lucilia caesar: two neutral glycosphingolipids having large straight oligosaccharide chains with eight and nine sugars.
J Biochem (Tokyo), 107, 899-903 (1990)

Nohara K, Suzuki M, Inagaki F, Ito H, Kaya K.
Identification of novel gangliosides containing lactosaminyl-GM1 structure from rat spleen.
J Biol Chem., 265, 14335-14339 (1990)

Kitagawa H, Nakada H, Numata Y, Kurosaka A, Fukui S, Funakoshi I, Kawasaki T, Shimada I, Inagaki F, Yamashina I.
Occurrence of tetra- and pentasaccharides with the sialyl-Le(a) structure in human milk.
J Biol Chem., 265, 4859-4862 (1990)

Kimura S, Tanaka T, Shimada I, Shiratori Y, Nakagawa S, Nakamura H, Inagaki F, Ota Y.
Deletion of D-helix in bovine pancreatic phospholipase A2.
Agric Biol Chem., 54, 633-639 (1990)

Hanzawa H, Shimada I, Kuzuhara T, Komano H, Kohda D, Inagaki F, Natori S, Arata Y.
1H nuclear magnetic resonance study of the solution conformation of an antibacterial protein, sapecin.
FEBS Lett., 269, 413-420 (1990)

Cooke RM, Tappin MJ, Campbell ID, Kohda D, Miyake T, Fuwa T, Miyazawa T, Inagaki F.
Nuclear-magnetic-resonance studies of human epidermal growth factor.
Eur J Biochem., 193, 807-815 (1990)

Inagaki F.
Three-dimensional structures of proteins determined by two-dimensional NMR and distance geometry calculations.
Cell Struct Funct. , 15, 237-243 (1990)

Inagaki F, Kohda D.
Tertiary Structures of Epidermal Growth Factor and Transforming Growth Factor a as Elucidated by Two-Dimensional NMR.
Protein Engineering., 59-62 (1990)

Shimada I, Inagaki F.
Binding modes of inhibitors of ribonuclease T1 as elucidated by analysis of two-dimensional NMR.
Biochemistry., 29, 757-764 (1990)

Endo T, Shimada I, Roise D, Inagaki F.
N-terminal half of a mitochondrial presequence peptide takes a helical conformation when bound to dodecylphosphocholine micelles: a proton nuclear magnetic resonance study.
J Biochem (Tokyo), 106, 396-400 (1989)

Kase R, Kitagawa H, Hayashi K, Tanoue K, Inagaki F.
Neutralizing monoclonal antibody specific for alpha-bungarotoxin: preparation and characterization of the antibody, and localization of antigenic region of alpha-bungarotoxin.
FEBS Lett., 254, 106-110 (1989)

Kitagawa H, Nakada H, Kurosawa A, Hiraiwa N, Numata Y, Fukui S, Ymashita I, Shimada I, Inagaki F.
Immunoaffinity Isolation of Three Novel Oligosaccharides with the sialyl-Lea Structure from Human Milk.
Biochemistry., 28, 8891-8897 (1989)

Sugita M, Itonori S, Inagaki F, Hori T.
Characterization of two glucuronic acid-containing glycosphingolipids in larvae of the green-bottle fly, Lucilia caesar.
J Biol Chem., 264, 15028-15033 (1989)

Hamanaka S, Asagami C, Suzuki M, Inagaki F, Suzuki A.
Structure determination of glucosyl beta 1-N-(omega-O-linoleoyl)-acylsphingosines of human epidermis.
J Biochem (Tokyo), 105, 684-690 (1989)

Inagaki F, Shimada I, Kawaguchi K, Hirano M, Terasawa I, Ikura T, Go N.
Structure of Melittin Bound to Perdeuterated Dodecylphosphocholine Micelles as Studied by 2D-NMR and Distance Geometry Calculations.
Biochemistry., 28, 5985-5991 (1989)

Inagaki F, Shimada I, Kohda D, Suzuki A, Bax A.
Relayed HOHAHA, a useful method for extracting subspectra of individual components of sugar chains.
J Magn Reson., 81, 186-190 (1989)

Inagaki F, Shimada I, Kawaguchi K, Terasawa I.
Structure of melittin bound to perdeuterated dodecylphosphocholine micelles as studied by 2D-NMR.
Peptide Chemistry., 263-266 (1989)

Kohda D, Shimada I, Miyake T, Fuwa T, Inagaki F.
Polypeptide chain fold of human transforming growth factor alpha analogous to those of mouse and human epidermal growth factors as studied by two-dimensional 1H NMR.
Biochemistry., 28, 953-958 (1989)

Muto Y, Inagaki F, Arata Y.
Proton nuclear magnetic resonance study of the solution conformation of C3a-Arg69, a 69-residue N-terminal fragment of the third component of complement.
J Biochem (Tokyo), 105, 330-337 (1989)

Ariga T, Suzuki M, Yu RK, Kuroda Y, Shimada I, Inagaki F, Miyatake T.
Accumulation of unique globo-series glycolipids in PC 12h pheochromocytoma cells.
J Biol Chem., 264, 1516-1521 (1989)

Shimada I, Inagaki F.
Binding modes of inhibitors to ribonuclease T1 as elucidated by the analysis of two-dimensional NMR.
Nucleic Acids Symp Ser., 57-58 (1989)

Kubo H, Irie A, Inagaki F, Hoshi M.
Melibiosylceramide as the sole ceramide dihexoside from the eggs of the sea urchin, Anthocidaris crassispina.
J Biochem (Tokyo), 104, 755-760 (1988)

Kitagawa H, Nakada H, Numata Y, Kurosaka A, Fukui S, Funakoshi I, Kawasaki T, Shimada K, Inagaki F, Yamashina I.
Immunoaffinity isolation of a sialyl-Le(a) oligosaccharide from human milk.
J Biochem (Tokyo), 104, 591-594 (1988)

Shibata Y, Shimada I, Ikehara M, Miyazawa T, Inagaki F.
1H-NMR investigation of the interaction between RNase T1 and a novel substrate analog, 2'-deoxy-2'-fluoroguanylyl-(3'-5')uridine.
FEBS Lett., 235, 237-240 (1988)

Nakamura K, Inagaki F, Tamai Y.
A novel ganglioside in dogfish brain. Occurrence of a trisialoganglioside with a sialic acid linked to N-acetylgalactosamine.
J Biol Chem., 263, 9896-9900 (1988)

Kohda D, Go N, Hayashi K, Inagaki F.
Tertiary structure of mouse epidermal growth factor determined by two-dimensional 1H NMR.
J Biochem (Tokyo), 103, 741-743 (1988)

Kohda D, Kodama C, Kase R, Nomoto H, Hayashi K, Inagaki F.
A comparative 1H NMR study of mouse alpha(1-53) and beta(2-53) epidermal growth factors.
Biochem Int., 16, 647-654 (1988)

Sekine M, Nakamura K, Suzuki M, Inagaki F, Yamakawa T, Suzuki A.
A single autosomal gene controlling the expression of the extended globoglycolipid carrying SSEA-1 determinant is responsible for the expression of two extended globogangliosides.
J Biochem (Tokyo), 103, 722-729 (1988)

Kohda D, Inagaki F.
Complete sequence-specific 1H nuclear magnetic resonance assignments for mouse epidermal growth factor.
J Biochem (Tokyo), 103, 554-571 (1988)

Ariga T, Kobayashi K, Kuroda Y, Yu RK, Suzuki M, Kitagawa H, Inagaki F, Miyatake T.
Characterization of tumor-associated fucogangliosides from PC 12 pheochromocytoma cells.
J Biol Chem., 262, 14146-14153 (1987)

Inagaki F, Kodama C, Suzuki M, Suzuki A.
Analysis of NMR spectra of sugar chains of glycolipids by 1D homonuclear Hartmann-Hahn and NOE experiments.
FEBS Lett., 219, 45-50 (1987)

Nakamura K, Suzuki M, Inagaki F, Yamakawa T, Suzuki A.
A new ganglioside showing choleragenoid-binding activity in mouse spleen.
J Biochem (Tokyo), 101, 825-835 (1987)

Sekine M, Suzuki M, Inagaki F, Suzuki A, Yamakawa T.
A new extended globoglycolipid carrying the stage specific embryonic antigen-1 (SSEA-1) determinant in mouse kidney.
J Biochem (Tokyo), 101, 553-562 (1987)

Inagaki F, Kohda D, Kodama C, Suzuki A.
Analysis of NMR spectra of sugar chains of glycolipids by multiple relayed COSY and 2D homonuclear Hartman-Hahn spectroscopy.
FEBS Lett., 212, 91-97 (1987)

Inagaki F.
Structure and Dynamics of Neurotoxins from Snake Venoms as Revealed by Nuclear Magnetic Resonance and Circular Dichroism.
J Toxicol-Toxin Reviews., 5, 105-123 (1986)

Inagaki F, Shimada I.
Hexacyanochromate ion as a paramagnetic anion probe for active sites of enzymes.
J Inorg Biochem., 28, 311-317 (1986)

Utsumi J, Yamazaki S, Hosoi K, Shimizu H, Kawaguchi K, Inagaki F.
Conformations of fibroblast and E. coli-derived recombinant human interferon-beta s as studied by nuclear magnetic resonance and circular dichroism.
J Biochem (Tokyo), 99, 1533-1535 (1986)

Inagaki F, Abe A.
Analysis of 1H and 13C Nuclear Magnetic Resonance Spectra of Spathulenol by Two-dimentional Methods.
J Chem Soc Perkin Trans II., 1773-1778 (1985)

Inagaki F, Hider RC, Hodges SJ, Drake AF.
Molecular conformation of alpha-bungarotoxin as studied by nuclear magnetic resonance and circular dichroism.
J Mol Biol., 183, 575-590 (1985)

Inagaki F, Shimada I, Miyazawa T.
Binding modes of inhibitors to ribonuclease T1 as studied by nuclear magnetic resonance.
Biochemistry., 24, 1013-1020 (1985)

Miyazawa T, Endo T, Inagaki F, Hayashi K, Tamiya N.
NMR analysis of structure and function of snake neurotoxins.
Biopolymers., 22, 139-145 (1983)

Endo T, Shimada I, Inagaki F, Miyazawa T.
Bronsted Relation for Hydrogen-Deuterium Exchange Reactions of Imidazole-bearing Molecules with Amino Groups.
Bull Chem Soc Japan., 56, 667-670 (1983)

Hider RC, Drake AF, Inagaki F, Williams RJ, Endo T, Miyazawa T.
Molecular Conformation of α-Cobratoxin as Studied by Nuclear Magnetic Resonance and Circular Dichroism.
J Mol Biol., 158, 275-291 (1982)

Inagaki F, Miyazawa T, Tamiya N, Williams RJ.
Structural Dynamics of Erabutoxin b. A 13C Nuclear Magnetic Reso-nance Relaxation Study of Methyl Groups.
Eur J Biochem., 123, 275-282 (1982)

Clayden NJ, Inagaki F, Williams RJ, Morris GA, Tori K, Tokura K, Miyazawa T.
Two Dimentional NMR Spectroscopy of Siomycin A. Proton-Carbon-13 Chemical Shift Correlation.
Eur J Biochem., 123, 127-131 (1982)

Inagaki F, Clayden NJ, Tamiya N, Williams RJ.
Individual Assigments of the mide Proton Resonances Involved in the Triple Stranded Pleated b-sheet Structure of Long Neurotoxin, Laticauda semifaciata III from Laticauda semifasciata.
Eur J Biochem., 123, 99-104 (1982)

Endo T, Inagaki F, Hayashi K, Miyazawa T.
Local Conformational Transition of Toxin B from Naja naja as Studied by Nuclear Magnetic Resonance and Circular Dichroism.
Eur J Biochem., 122, 541-547 (1982)

Inagaki F, Boyd J, Cambell ID, Clayden NJ, Hull WE, Tamiya N, Williams RJ.
Dynamics of Erabutoxin b as Studied by Neuclear Magnetic Resonance.
Eur J Biochem., 121, 609-616 (1982)

Inagaki F, Clayden NJ, Tamiya N, Williams RJ.
A Proton-Magnetic-Resonance Study on the Molecular Conformation and Structure-Function Relationship of a Long Neurotoxin, Laticauda semifasciata III from Laticauda Semifasciata.
Eur J Biochem., 120, 313-322 (1981)

Inagaki F, Miyazawa T, Williams RJ.
The Dynamic Structures of Proteins: Short and Long Neuratoxins as Examples.
Bioscience Rep., 1, 743-755 (1981)

Endo T, Inagaki F, Hayashi K, Miyazawa T.
Proton Nuclear Magnetic Resonance Study on Molecular Conformations of Long Neurotoxins, α-Bungarotoxin from Bungarus and Toxin B from Naja naja.
Eur J Biochem., 120, 117-124 (1981)

Inagaki F, Tamiya N, Miyazawa T, Williams RJ.
Structural Differences between Erabutoxins in Aqueous Solution and in Crystalline States.
Eur J Biochem., 118, 621-625 (1981)

Yokoyama S, Inagaki F, Miyazawa T.
Advanced Nuclear Magnetic Resonance Lanthanide Probe Analyses of Short-Range Conformational Interrelations Controlling Ribonucleic Acid Structures.
Biochemistry., 20, 2982-2988 (1981)

Inagaki F, Miyazawa T.
NMR Analyses of Molecular Conformations and Conformational Equilibria with Lanthanide Probe Method.
Prog Nuclear Magn Reson Spectrosc., 14, 67-111 (1981)

Inagaki F, Kawano Y, Shimada I, Takahashi K, Miyazawa T.
Nuclear Magnetic Resonance study on the Microenvironments of Histidine Residues of Ribonuclease T1 and Carboxythylated Ribonuclease T1.
J Biochem (Tokyo), 89, 1185-1195 (1981)

Tori K, Tokura K, Yoshimura Y, Terui Y, Okabe K, Otsuka H, Matsushita K, Inagaki F, Miyazawa T.
Structure of Siomycin-B and -C and Thiostrepton-B Determined by NMR spectroscopy and Carbon-13 Signal Assignmnets Siomycins, Thiostreptons and Thiopeptin-B.
J Antibiot (Tokyo)., 34, 124-129 (1981)

Tamiya N, Takasaki C, Sato A, Menez A, Inagaki F, Miyazawa T.
Structure and function of erabutoxins and related neurotoxins from sea snakes and cobras.
Biochem Soc Trans., 8, 753-755 (1980)

Tokura K, Tori K, Yoshimura Y, Okabe K, Otsuka H, Matsushita K, Inagaki F, Miyazawa T.
The structure of siomycin-D1, peptide antibiotic isolated from Streptomyces sioyaensis.
J Antibiot (Tokyo)., 33, 1563-1567 (1980)

Inagaki F, Tamiya N, Miyazawa T.
Molecular conformation and function of erabutoxins as studied by nuclear magnetic resonance.
Eur J Biochem., 109, 129-138 (1980)

Okabe K, Tokura K, Hayashi K, Tori K, Terui Y, Yoshimura Y, Otsuka H, Matsushita K, Inagaki F, Miyazawa T.

Peptide Chemistry., 19-24 (1979)

Endo T, Inagaki F, Hayashi K, Miyazawa T.
Conformation of Cobrotoxin in Aqueous Solution as Studied by Nuclear Magnetic Resonance.
Eur J Biochem., 102, 417-430 (1979)

Tori K, Tokura K, Yoshimura Y, Okabe K, Otsuka H, Inagaki F, Miyazawa T.
1H NMR Spectral Evidence for the Structure and Conformation of Peptide Antibiotic Siomycin-A.
J Antibiot (Tokyo)., 32, 1072-1077 (1979)

Inagaki F, Watanabe K, Miyazawa T.
Hexacyanochromate Ion as a Paramagnetic Anion Probe for Active Sites of Ezymes: Application to Ribonuclease A.
J Biochem (Tokyo), 86, 591-594 (1979)

Inagaki F, Miyazawa T, Miwa M, Saito H, Sugimura T.
NMR analyses of conformation of ribosyl adenosine 5',5''-bis(phosphate) in aqueous solution.
Biochem Biophys Res Commun., 85, 415-420 (1978)

Inagaki F, Miyazawa T, Hori H, Tamiya N.
Conformation of Erabutoxins a and b in Aqueous Solution as Studied by Nuclear Magnetic Resonance and Circular Dichroism.
Eur J Biochem., 89, 433-442 (1978)

Inagaki F, Miyazawa T, Yanaihara N, Otsuka M.
Substance P Analogs: NMR Spectra and Conformations in Solutions.
Peptide Chemistry., 103-108 (1978)

Inagaki F, Tatsumi M, Miyazawa T.
Structure and Populations of Conformaers of Nucleoside Monophosphates in Aqueous Solution. I. General Methods of Conformation Search with Lanthanide-Ion Probes and Spin-Coupling Constants and Application to Uridine-5' Monophosphate.
Biopolymers., 17, 267-289 (1978)

Oida F, Yokoyama S, Inagaki F, Tatsumi M, Miyazawa T.
Molecular Structure of NMN and UpU in Aqueous Solution as Studied by the lanthanide-Ion Probe Method.
Nucleic Acid Res., Spec Pub., No.2, s47-s50 (1977)

Inagaki F, Tasumi M, Miyazawa T.
Use of Gd(fod)-3 Induced Changes of 1H Relaxation Times in Conformation Studies of the Complexes between Lanthanide Chelates and Borneols.
J Magn Reson., 27, 91-99 (1977)

Nakao A, Inagaki F, Tasumi M, Miyazawa T.
1H Spin-Lattice Relaxation Times of Imidazole and L-Histidine Treated with a Metal-Chelating Resin.
J C Chem Comm., 7, 232-233 (1976)

Inagaki F, Takahashi S, Tasumi M, Miyazawa T.
Conformation of Thymidine 3',5'-Cyclic Phosphate in Aqueous Solution. Compatibility of the Information from the Lanthanide lon Probe and Spin Coupling Constants.
Bull Chem Soc Japan., 49, 611-616 (1976)

Inagaki F, Tasumi M, Miyazawa T.
Conformation of Hydroxy-L-proline in Aqueous Solution. Comparison of Results from Lanthanide lon probe Measurements and Proton Coupling Constants.
J Chem Soc Perkin Trans II., 2, 167-172 (1976)

Sakakibara M, Inagaki F, Harada I, Shimanouchi T.
Vibrational Spectra and Rotational Isomerism of Alkyl Vinyl Ethers.
Bull Chem Soc Japan., 49, 46-52 (1976)

Inagaki F, Sakakibara M, Harada, I, Shimanouchi T.
Infrared and Raman Spectra and Rotational Isomerism of 1,4-Pentafiene.
Bull Chem Soc Japan., 48, 3557-3560 (1975)

Inagaki F, Tasumi M, Miyazawa T.
Vibrational Analysis of Polyene Chains.
J Raman Spectrosc., 3, 335-343 (1975)

Inagaki F, Takahashi S, Tasumi, M, Miyazawa T.
Lanthanide-Induced Nuclear Magnetic Resonance Shifts and Molecular Structure of L-Azetidine-2-Carboxylic Acid. II. Determination of Molecular Conformation.
Bull Chem Soc Japan., 48, 1590-1594 (1975)

Inagaki F, Tasumi M, Miyazawa T.
Chemical Equilibrium between a Lanthanide Shift Reagent and n-Hexylamine in Chloroform.
Bull Chem Soc Japan., 48, 1427-1430 (1975)

Inagaki F, Takahashi S, Tasumi M, Miyazawa T.
Lanthanide-Induced Nuclear Magnetic Resonance Shifts and Molecular Structure of L-Azetidine-2-Carboxylic Acid. I. Evaluation of the Shifts Intrinsic to the Lanthanide Substrate 1:1 Complex.
Bull Chem Soc Japan., 48, 853-856 (1975)

Inagaki F, Tasumi M, Miyazawa T.
Excitation Profile of the Resonance Raman Effect of βcarotene
J Mol Spectrosc., 50, 286-303 (1974)

Tasumi M, Inagaki F, Miyazawa T.
Resonance Raman Spectra of β-carotene and Its Molecular Structure in the Excited Electronic State.
Chem Phys Lett., 22, 515-518 (1973)

Inagaki F, Harada I, Shimanouchi T.
Far Infrared Spectra and Barriers to Internal Rotation of Isopropyl Alchohl and Alkyl Mercaptans.
J Mol Spectrosc., 46, 381-396 (1973)

Inagaki F, Harada I, Shimanouchi T, Tasumi M.
Resonance Raman Spectra of Poly(vinyl alcohol)-lodine Complex.
‘Advance in Raman Spectroscopy’ J. P. Mathieu, ed., Hyden & Son Ltd., London, 1, 370-378 (1973)

Inagaki F, Harada I, Shimanouchi T, Tasumi M.
The Resonance Raman Spectra of Poly(vinyl alcohol)-lodine Complex.
Bull Chem Soc Japan., 45, 3384-3388 (1972)

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