北大構造生物学研究室

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Saio T, Hiramatsu S, Asada M, Nakagawa H, Shimizu K, Kumeta H, Nakamura T, Ishimori K.
Conformational ensemble of a multidomain protein explored by Gd3+ electron paramagnetic resonance.
Biophys J. 120 2943-2951 (2021)

Mimura M, Tomita S, Shinkai Y, Hosokai T, Kumeta H, Saio T, Shiraki K, Kurita R.
Quadruplex Folding Promotes the Condensation of Linker Histones and DNAs via Liquid-Liquid Phase Separation.
J Am Chem Soc. 143 9849-9857 (2021)

Okumura M, Kanemura S, Matsusaki M, Kinoshita M, Saio T, Ito D, Hirayama C, Kumeta H, Watabe M, Amagai Y, Lee YH, Akiyama S, Inaba K.
A unique leucine-valine adhesive motif supports structure and function of protein disulfide isomerase P5 via dimerization.
Structure 29 1357-1370 (2021)

Yoza K, Himeno R, Amano S, Kobashigawa Y, Amemiya S, Fukuda N, Kumeta H, Morioka H, Inagaki F.
Biophysical characterization of drug-resistant mutants of fibroblast growth factor receptor 1.
Genes Cells. (2016)

Yamasaki A, Watanabe Y, Adachi W, Suzuki K, Matoba K, Kirisako H, Kumeta H, Nakatogawa H, Ohsumi Y, Inagaki F, Noda NN.
Structural Basis for Receptor-Mediated Selective Autophagy of Aminopeptidase I Aggregates.
Cell Rep. 28 19-27 (2016)

Kobashigawa Y, Amano S, Yoza K, Himeno R, Amemiya S, Morioka H, Yokogawa M, Kumeta H, Schlessinger J, Inagaki F.
Nuclear magnetic resonance analysis of the conformational state of cancer mutant of fibroblast growth factor receptor 1 tyrosine kinase domain.
Genes Cells. 21 350-357 (2016)

Yokogawa M, Tsushima T, Noda NN, Kumeta H, Enokizono Y, Yamashita K, Standley DM, Takeuchi O, Akira S, Inagaki F.
Structural basis for the regulation of enzymatic activity of Regnase-1 by domain-domain interactions.
Sci Rep. 6 22324 (2016)

Noda NN, Inagaki F.
Mechanisms of Autophagy.
Annu Rev Biophys. 44 101-122 (2015)

Mazhab-Jafari MT, Marshall CB, Smith MJ, Gasmi-Seabrook GM, Stathopulos PB, Inagaki F, Kay LE, Neel BG, Ikura M.
Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site.
Proc Natl Acad Sci U S A. 112 6625-6630 (2015)

Yamamoto H, Shima T, Yamaguchi M, Mochizuki Y, Hoshida H, Kakuta S, Kondo-Kakuta C, Noda NN, Inagaki F, Itoh T, Akada R, Ohsumi Y.
The Thermotolerant Yeast Kluyveromyces marxianus Is a Useful Organism for Structural and Biochemical Studies of Autophagy.
J Biol Chem. 290 29506-29518 (2015)

Funami K, Matsumoto M, Enokizono Y, Ishii N, Tatematsu M, Oshiumi H, Inagaki F, Seya T.
Identification of a Regulatory Acidic Motif as the Determinant of Membrane Localization of TICAM-2.
J Immunol. 195 4456-4465 (2015)

Imai M, Saio T, Kumeta H, Uchida T, Inagaki F, Ishimori K.
Investigation of the redox-dependent modulation of structure and dynamics in human cytochrome c.
Biochem Biophys Res Commun. 469 978-984 (2015)

Saio T, Ogura K, Kumeta H, Kobashigawa Y, Shimizu K, Yokochi M, Kodama K, Yamaguchi H, Tsujishita H, Inagaki F
Ligand-driven conformational changes of MurD visualized by paramagnetic NMR.
Sci Rep. 5 16685 (2015)

Kobashigawa Y, Amano S, Yokogawa M, Kumeta H, Morioka H, Inouye M, Schlessinger J, Inagaki F.
Structural analysis of the mechanism of phosphorylation of a critical autoregulatory tyrosine residue in FGFR1 kinase domain.
Genes Cells. 20 860-870 (2015)

Fujioka Y, Suzuki SW, Yamamoto H, Kondo-Kakuta C, Kimura Y, Hirano H, Akada R, Inagaki F, Ohsumi Y, Noda NN.
Structural basis of starvation-induced assembly of the autophagy initiation complex.
Nat Struct Mol Biol. 21 513-521 (2014)

Suzuki K, Nakamura S, Morimoto M, Fujii K, Noda NN, Inagaki F, Ohsumi Y.
Proteomic profiling of autophagosome cargo in Saccharomyces cerevisiae.
PLoS One. 9 e91651 (2014)

Kumeta H, Sakakibara H, Enokizono Y, Ogura K, Horiuchi M, Matsumoto M, Seya T, Inagaki F.
The N-terminal domain of TIR domain-containing adaptor molecule-1, TICAM-1.
J Biomol NMR. 58 227-230 (2014)

Enokizono Y, Kumeta H, Funami K, Horiuchi M, Sarmiento J, Yamashita K, Standley DM, Matsumoto M, Seya T, Inagaki F.
Structures and interface mapping of the TIR domain-containing adaptor molecules involved in interferon signaling.
Proc Natl Acad Sci U S A. 110 19908-19913 (2013)

Tamura N, Oku M, Ito M, Noda NN, Inagaki F, Sakai Y.
Atg18 phosphoregulation controls organellar dynamics by modulating its phosphoinositide-binding activity.
J Cell Biol. 202 685-698 (2013)

Ogura K, Kobashigawa Y, Saio T, Kumeta H, Torikai S, Inagaki F.
Practical applications of hydrostatic pressure to refold proteins from inclusion bodies for NMR structural studies.
Protein Eng Des Sel. 26 409-416 (2013)

Kumeta H, Ogura K, Nishimiya Y, Miura A, Inagaki F, Tsuda S.
NMR structure note: a defective isoform and its activity-improved variant of a type III antifreeze protein from Zoarces elongates Kner.
J Biomol NMR. 55 225-230 (2013)

Noda NN, Fujioka Y, Hanada T, Ohsumi Y, Inagaki F.
Structure of the Atg12-Atg5 conjugate reveals a platform for stimulating Atg8-PE conjugation.
EMBO Rep. 14 206-211 (2013)

Yamaguchi M, Matoba K, Sawada R, Fujioka Y, Nakatogawa H, Yamamoto H, Kobashigawa Y, Hoshida H, Akada R, Ohsumi Y, Noda NN, Inagaki F.
Noncanonical recognition and UBL loading of distinct E2s by autophagy-essential Atg7.
Nat Struct Mol Biol. 19 1250-1256 (2012)

Yokogawa M, Kobashigawa Y, Yoshida N, Ogura K, Harada K, Inagaki F.
NMR analyses of the interaction between the EEA1 FYVE domain and phosphoinositide embedded in lipid bilayer.
J Biol Chem. 287 34936-34945 (2012)

Horiuchi M, Takahasi K, Kobashigawa Y, Ochiai M, Inagaki F.
A low-cost affinity purification system using β-1,3-glucan recognition protein and curdlan beads.
Protein Eng Des Sel. 25 405-413 (2012)

Ogura K, Okamura H, Katahira M, Katoh E, Inagaki F.
Conformational dynamics of yeast calmodulin in the Ca(2+)-bound state probed using NMR relaxation dispersion.
FEBS Lett. 586 2548-2554 (2012)

Yamaguchi M, Noda NN, Yamamoto H, Shima T, Kumeta H, Kobashigawa Y, Akada R, Ohsumi Y, Inagaki F.
Structural Insights into Atg10-Mediated Formation of the Autophagy-Essential Atg12-Atg5 Conjugate.
Structure 20 1244-1254 (2012)

Kobashigawa Y, Inagaki F.
Structural biology: CrkL is not Crk-like.
Nat Chem Biol. 8 504-505 (2012)

Kobashigawa Y, Saio T, Ushio M, Sekiguchi M, Yokochi M, Ogura K, Inagaki F.
Convenient method for resolving degeneracies due to symmetry of the magnetic susceptibility tensor and its application to pseudo contact shift-based protein-protein complex structure determination.
J Biomol NMR. 53 53-63 (2012)

Noda NN, Kobayashi T, Adachi W, Fujioka Y, Ohsumi Y, Inagaki F.
Structure of the Novel C-terminal Domain of Vacuolar Protein Sorting 30/Autophagy-related Protein 6 and Its Specific Role in Autophagy.
J Biol Chem. 287 16256-16266 (2012)

Kondo-Okamoto N, Noda NN, Suzuki SW, Nakatogawa H, Takahashi I, Matsunami M, Hashimoto A, Inagaki F, Ohsumi Y, Okamoto K.
Autophagy-related Protein 32 Acts as Autophagic Degron and Directly Initiates Mitophagy.
J Biol Chem. 287 10631-10638 (2012)

Ogura K, Kumeta H, Takahasi K, Kobashigawa Y, Yoshida R, Itoh H, Yazawa M, Inagaki F.
Solution structures of yeast Saccharomyces cerevisiae calmodulin in calcium- and target peptide-bound states reveal similarities and differences to vertebrate calmodulin.
Genes Cells. 17 159-172 (2012)

Kobashigawa Y, Tomitaka A, Kumeta H, Noda NN, Yamaguchi M, Inagaki F.
Autoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-b.
Proc Natl Acad Sci U S A. 108 20579-20584 (2011)

Saio T, Ogura K, Shimizu K, Yokochi M, Burke TR Jr, Inagaki F.
An NMR strategy for fragment-based ligand screening utilizing a paramagnetic lanthanide probe.
J Biomol NMR 51 395-408 (2011)

Noda NN, Satoo K, Fujioka Y, Kumeta H, Ogura K, Nakatogawa H, Ohsumi Y, Inagaki F.
Structural basis of Atg8 activation by a homodimeric E1, Atg7.
Mol Cell 44 462-475 (2011)

Sekiguchi M, Kobashigawa Y, Kawasaki M, Yokochi M, Kiso T, Suzumura KI, Mori K, Teramura T, Inagaki F.
An evaluation tool for FKBP12-dependent and -independent mTOR inhibitors using a combination of FKBP-mTOR fusion protein, DSC and NMR.
Protein Eng Des Sel. 24 811-817 (2011)

Kobashigawa Y, Harada K, Yoshida N, Ogura K, Inagaki F
Phosphoinositide-incorporated lipid-protein nanodiscs: A tool for studying protein-lipid interactions.
Anal Biochem 410 77-83 (2011)

Watanabe Y, Noda NN, Kumeta H, Suzuki K, Ohsumi Y, Inagaki F.
Selective transport of alpha-mannosidase by autophagic pathways: structural basis for cargo recognition by ATG19 and ATG34.
J Biol Chem 285 30026-30033 (2010)

Yamaguchi M, Noda NN, Nakatogawa H, Kumeta H, Ohsumi Y, Inagaki F.
Autophagy-related protein (Atg) 8-family interacting motif in Atg3 mediates the Atg3-Atg8 interaction and is crucial for the cytoplasm-to-vacuole targeting pathway.
J Biol Chem 285 29599-29607 (2010)

Ogura K, Kumeta H, Inagaki F.
Structure determination of proteins in (2)H (2)O solution aided by a deuterium-decoupled 3D HCA(N)CO experiment.
J Biomol NMR 47 243-248 (2010)

Takaku T, Ogura K, Kumeta H, Yoshida N, Inagaki F.
Solution structure of a novel Cdc42-binding module of Bem1 and its interaction with Ste20 and Cdc42.
J Biol Chem 285 19346-19353 (2010)

Kumeta H, Watanabe M, Nakatogawa H, Yamaguchi M, Ogura K, Adachi W, Fujioka Y, Noda NN, Ohsumi Y, Inagaki F.
The NMR structure of the autophagy-related protein Atg8.
J Biomol NMR 47 237-241 (2010)

Fujii K, Nakamura S, Takahashi K, Inagaki F.
Systematic characterization by mass spectrometric analysis of phosphorylation sites in IRF-3 regulatory domain activated by IKK-i.
J Proteomics. 73 1196-1203 (2010)

Noda NN, Ohsumi Y, Inagaki F.
Atg8-family interacting motif crucial for selective autophagy
FEBS Lett 584 1379-1385 (2010)

Saio T, Yokochi M, Kumeta H, Inagaki F.
PCS-based structure determination of protein-protein complexes.
J Biomol NMR 46 271-280 (2010)

Kumeta H, Miwa N, Ogura K, Kai Y, Mizukoshi T, Shimba N, Suzuki EI, Inagaki F.
The NMR structure of protein-glutaminase from Chryseobacterium proteolyticum.
J Biomol NMR 46 251-255 (2010)

Fujioka Y, Noda NN, Nakatogawa H, Ohsumi Y, Inagaki F.
The dimeric coiled-coil structure of Saccharomyces cerevisiae Atg16 and its functional significance in autophagy.
J Biol Chem 285 1508-1515 (2010)

Takahasi K, Ochiai M, Horiuchi M, Kumeta H, Ogura K, Ashida M, Inagaki F.
Solution structure of the silkworm betaGRP/GNBP3 N-terminal domain reveals the mechanism for beta-1,3-glucan-specific recognition.
Proc Natl Acad Sci U S A. 106 11679-11684 (2009)

Kabeya Y, Noda NN, Fujioka Y, Suzuki K, Inagaki F, Ohsumi Y.
Characterization of the Atg17-Atg29-Atg31 complex specifically required for starvation-induced autophagy in Saccharomyces cerevisiae.
Biochem Biophys Res Commun. 389 612-615 (2009)

Saio T, Yokochi M, Inagaki F.
The NMR structure of the p62 PB1 domain, a key protein in autophagy and NF-kappaB signaling pathway.
J Biomol NMR 45 335-341 (2009)

Horiuchi M, Takeuchi K, Noda N, Muroya N, Suzuki T, Nakamura T, Kawamura-Tsuzuku J, Takahasi K, Yamamoto T, Inagaki F.
Structural basis for the antiproliferative activity of the Tob-hCaf1 complex.
J Biol Chem 284 13244-13255 (2009)

Saio T, Ogura K, Yokochi M, Kobashigawa Y, Inagaki F.
Two-point anchoring of a lanthanide-binding peptide to a target protein enhances the paramagnetic anisotropic effect.
J Biomol NMR 44 157-166 (2009)

Takahasi K, Kumeta H, Tsuduki N, Narita R, Shigemoto T, Hirai R, Yoneyama M, Horiuchi M, Ogura K, Fujita T, Inagaki F.
Solution structures of cytosolic RNA sensors MDA5 and LGP2 C-terminal domains: Identification of the RNA recognition loop in RIG-I like receptors.
J Biol Chem 284 17465-17474 (2009)

Ogura K, Tandai T, Yoshinaga S, Kobashigawa Y, Kumeta H, Ito T, Sumimoto H, Inagaki F.
NMR structure of the heterodimer of Bem1 and Cdc24 PB1 domains from Saccharomyces cerevisiae.
J Biochem (Tokyo) 146 317-325 (2009)

Watanabe Y, Noda NN, Honbou K, Suzuki K, Sakai Y, Ohsumi Y, Inagaki F
Crystallization of Saccharomyces cerevisiae alpha-mannosidase, a cargo protein of the Cvt pathway
Acta Crystallogr Sect F Struct Biol Cryst Commun 65 571-3 (2009)

Kobashigawa Y, Kumeta H, Kanoh D, Inagaki F
The NMR structure of the TC10- and Cdc42-interacting domain of CIP4
J Biomol NMR 44 113-118 (2009)

Satoo K, Noda NN, Kumeta H, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F.
The structure of Atg4B-LC3 complex reveals the mechanism of LC3-processing and delipidation during autophagy
EMBO J. 28 1341-1350 (2009)

Kobashigawa Y, Kumeta H, Ogura K, Inagaki F
Attachment of an NMR-invisible solubility enhancement tag using a sortase-mediated protein ligation method.
J Biomol NMR 43 145-150 (2009)

Noda NN, Ohsumi Y, Inagaki F.
Atg systems from the protein structural point of view,
Chem. Rev. 109 1587-1598 (2009)

Noda NN, Kumeta H, Nakatogawa H, Satoo K, Adachi W, Ishii J, Fujioka Y, Ohsumi Y, Inagaki F.
Structural basis of target recognition by Atg8/LC3 during selective autophagy.
Genes Cells 13 1211-1218 (2008)

Fujioka Y, Noda NN, Matsushita M, Ohsumi Y, Inagaki F
Crystallization of the coiled-coil domain of Atg16 essential for autophagy
Acta Crystallogr Sect F Struct Biol Cryst Commun. 64 1046-1048 (2008)

Kumeta H, Ogura K, Adachi S, Fujioka Y, Tanuma N, Kikuchi K, Inagaki F.
The NMR structure of the NIPP1 FHA domain.
J Biomol NMR 40 219-224 (2008)

Takahasi K, Yoneyama M, Nishihori T, Hirai R, Kumeta H, Narita R, Gale M Jr, Inagaki F, Fujita T.
Nonself RNA-Sensing Mechanism of RIG-I Helicase and Activation of Antiviral Immune Responses.
Mol Cell 29 428-440 (2008)

Fujioka Y, Noda NN, Fujii K, Yoshimoto K, Ohsumi Y, Inagaki F.
In vitro reconstitution of plant ATG8 and ATG12 conjugation systems essential for autophagy
J Biol Chem 283 1921-1928 (2008)

Noda NN, Fujioka Y, Ohsumi Y, Inagaki F.
Crystallization of the Atg12-Atg5 conjugate bound to Atg16 by the free interface diffusion method.
J Synchrotron Radiat. 15 266-268 (2008)

Hanada T, Noda NN, Satomi Y, Ichimura Y, Fujioka Y, Takao T, Inagaki F, Ohsumi Y.
The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy.
J Biol Chem 282 37298-37302 (2007)

Kumeta H, Ogura K, Asayama M, Katoh S, Katoh E, Teshima K, Inagaki F.
The NMR structure of the domain II of a chloroplastic NifU-like protein OsNifU1A.
J Biomol NMR 38 161-164 (2007)

Saio T, Kumeta H, Ogura K, Yokochi M, Asayama M, Katoh S, Katoh E, Teshima K, Inagaki F.
The Cooperative Role of OsCnfU-1A Domain I and Domain II in the Iron Sulphur Cluster Transfer Process as Revealed by NMR.
J Biochem (Tokyo) 142 113-121 (2007)

Honbou K, Minakami R, Yuzawa S, Takeya R, Suzuki NN, Kamakura S, Sumimoto H, Inagaki F.
Full-length p40phox structure suggests a basis for regulation mechanism of its membrane binding.
EMBO J. 26 1176-1186 (2007)

Kobashigawa Y, Naito M, Inagaki F.
An efficient method for protein phosphorylation using the artificially introduction of cognate binding modules into kinases and substrates.
J Biotechnol. 131 458-465 (2007)

Kobashigawa Y, Sakai M, Naito M, Yokochi M, Kumeta H, Makino Y, Ogura K, Tanaka S, Inagaki F.
Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK.
Nat Struct Mol Biol. 14 503-510 (2007)

Matsushita M, Suzuki NN, Obara K, Fujioka Y, Ohsumi Y, Inagaki F.
Structure of Atg5.Atg16, a complex essential for autophagy.
J Biol Chem 282 6763-6772 (2007)

Yamada Y, Suzuki NN, Hanada T, Ichimura Y, Kumeta H, Fujioka Y, Ohsumi Y, Inagaki F.
The crystal structure of Atg3, an autophagy-related ubiquitin carrier protein (E2) enzyme that mediates Atg8 lipidation.
J Biol Chem 282 8036-8043 (2007)

Satoo K, Suzuki NN, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F.
Crystallization and preliminary crystallographic analysis of human Atg4B-LC3 complex.
Acta Crystallograph Sect F Struct Biol Cryst Commun. 63 99-102 (2007)

Adachi W, Suzuki NN, Fujioka Y, Suzuki K, Ohsumi Y, Inagaki F.
Crystallization of Saccharomyces cerevisiae aminopeptidase 1, the major cargo protein of the Cvt pathway.
Acta Crystallograph Sect F Struct Biol Cryst Commun. 63 200-203 (2007)

Yamaguti M, Suzuki NN, Fujioka Y, Ohsumi Y, Inagaki F.
Crystallization and preliminary X-ray analysis of Atg10.
Acta Crystallograph Sect F Struct Biol Cryst Commun. 63 443-445 (2007)

Ogura K, Nobuhisa I, Yuzawa S, Takeya R, Torikai S, Saikawa K, Sumimoto H, Inagaki F.
NMR solution structure of the tandem Src homology 3 domains of p47phox complexed with a p22phox-derived proline-rich peptide.
J Biol Chem 281 3660-3668 (2006)

Yamada Y, Suzuki NN, Fujioka Y, Ichimura Y, Ohsumi Y, Inagaki F.
Crystallization and preliminary X-ray analysis of Atg3.
Acta Crystallograph Sect F Struct Biol Cryst Commun. 62 1016-1017 (2006)

Honbou K, Yuzawa S, Suzuki NN, Fujioka Y, Sumimoto H, Inagaki F.
Crystallization and preliminary crystallographic analysis of p40phox, a regulatory subunit of NADPH oxidase.
Acta Crystallograph Sect F Struct Biol Cryst Commun. 62 1018-1020 (2006)

Matsushita M, Suzuki NN, Fujioka Y, Ohsumi Y, Inagaki F.
Expression, purification and crystallization of the Atg5-Atg16 complex essential for autophagy.
Acta Crystallograph Sect F Struct Biol Cryst Commun. 62 1021-1023 (2006)

Yoshida S, Ogura K, Yokochi M, Yuzawa S, Horiuchi M, Morioka H, Sumimoto H, Inagaki F.
1H, 13C and 15N resonance assignments of the backbone and methyl groups of the 24 kDa tetratricopeptide repeat domain in p67(phox).
J Biomol NMR 32 176 (2005)

Hirano Y, Yoshinaga S, Takeya R, Suzuki NN, Horiuchi M, Kohjima M, Sumimoto H, Inagaki F.
Structure of a cell polarity regulator, a complex between atypical PKC and Par6 PB1 domains.
J Biol Chem 280 9653-9661 (2005)

Kamada Y, Fujioka Y, Suzuki NN, Inagaki F, Wullschleger S, Loewith R, Hall MN, Ohsumi Y.
Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization.
Mol Cell Biol. 25 7239-7248 (2005)

Sugawara K, Suzuki NN, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F.
Structural basis for the specificity and catalysis of human Atg4B responsible for mammalian autophagy.
J Biol Chem 280 40058-40065 (2005)

Suzuki NN, Yoshimoto K, Fujioka Y, Ohsumi Y, Inagaki F.
The crystal structure of plant ATG12 and its biological implication in autophagy.
Autophagy 1 119-126 (2005)

Hirano Y, Yoshinaga S, Ogura K, Yokochi M, Noda Y, Sumimoto H, Inagaki F.
Solution structure of atypical protein kinase C PB1 domain and its mode of interaction with ZIP/p62 and MEK5.
J Biol Chem 279 31883-31890 (2004)

Suzuki NN, Koizumi K, Fukushima M, Matsuda A, Inagaki F.
Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase.
Structure 12 751-764 (2004)

Hashida S, Yuzawa S, Suzuki NN, Fujioka Y, Takikawa T, Sumimoto H, Inagaki F, Fujii H.
Binding of FAD to cytochrome b558 is facilitated during activation of the phagocyte NADPH oxidase, leading to superoxide production.
J Biol Chem 279 26378-26386 (2004)

Yuzawa S, Ogura K, Horiuchi M, Suzuki NN, Fujioka Y, Kataoka M, Sumimoto H, Inagaki F.
Solution structure of the tandem Src homology 3 domains of p47phox in an autoinhibited form.
J Biol Chem 279 29752-29760 (2004)

Yuzawa S, Suzuki NN, Fujioka Y, Ogura K, Sumimoto H, Inagaki F.
A molecular mechanism for autoinhibition of the tandem SH3 domains of p47phox, the regulatory subunit of the phagocyte NADPH oxidase.
Genes Cells 9 443-456 (2004)

Yuzawa S, Yokochi M, Fujioka Y, Ogura K, Sumimoto H, Inagaki F.
Sequence-specific resonance assignments of the tandem SH3 domains in an autoinhibitory form of p47(phox).
J Biomol NMR 29 451-452 (2004)

Sugawara K, Suzuki NN, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F.
The crystal structure of microtubule-associated protein light chain 3, a mammalian homologue of Saccharomyces cerevisiae Atg8.
Genes Cells 9 611-618 (2004)

Yuzawa S, Ogura K, Hatanaka H, Miura K, Inagaki F.
Backbone assignments of Grb2 complexed with ligand peptides for SH3 and SH2 domains.
J Biomol NMR 27 185-186 (2003)

Yoshinaga S, Kohjima M, Ogura K, Yokochi M, Takeya R, Ito T, Sumimoto H, Inagaki F.
The PB1 domain and the PC motif-containing region are structurally similar protein binding modules.
EMBO J. 22 4888-4897 (2003)

Honbou K, Suzuki NN, Horiuchi M, Niki T, Taira T, Ariga H, Inagaki F.
The crystal structure of DJ-1, a protein related to male fertility and Parkinson's disease.
J Biol Chem 278 31380-31384 (2003)

Suzuki NN, Koizumi K, Fukushima M, Matsuda A, Inagaki F.
Crystallization and preliminary X-ray analysis of human uridine-cytidine kinase 2.
Acta Crystallogr D Biol Crystallogr. 59 1477-1478 (2003)

Honbou K, Suzuki NN, Horiuchi M, Taira T, Niki T, Ariga H, Inagaki F.
Crystallization and preliminary crystallographic analysis of DJ-1, a protein associated with male fertility and parkinsonism.
Acta Crystallogr D Biol Crystallogr. 59 1502-1503 (2003)

Takahasi K, Suzuki NN, Horiuchi M, Mori M, Suhara W, Okabe Y, Fukuhara Y, Terasawa H, Akira S, Fujita T, Inagaki F.
X-ray crystal structure of IRF-3 and its functional implications.
Nat Struct Biol. 10 922-927 (2003)

Sugawara K, Suzuki NN, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F.
Crystallization and preliminary X-ray analysis of LC3-I.
Acta Crystallogr D Biol Crystallogr. 59 1464-1465 (2003)

Yuzawa S, Suzuki NN, Fujioka Y, Ogura K, Sumimoto H, Inagaki F.
Crystallization and preliminary crystallographic analysis of the autoinhibited form of the tandem SH3 domain of p47(phox).
Acta Crystallogr D Biol Crystallogr. 59 1479-1480 (2003)

Ogura K, Nagata K, Horiuchi M, Ebisui E, Hasuda T, Yuzawa S, Nishida M, Hatanaka H, Inagaki F.
Solution structure of N-terminal SH3 domain of Vav and the recognition site for Grb2 C-terminal SH3 domain.
J Biomol NMR 22 37-46 (2002)

Terasawa H, Noda Y, Ito T, Hatanaka H, Ichikawa S, Ogura K, Sumimoto H, Inagaki F.
Structure and ligand recognition of the PB1 domain: a novel protein module binding to the PC motif.
EMBO J. 20 3947-3956 (2001)

Nishida M, Nagata K, Hachimori Y, Horiuchi M, Ogura K, Mandiyan V, Schlessinger J, Inagaki F.
Novel recognition mode between Vav and Grb2 SH3 domains.
EMBO J. 20 2995-3007 (2001)

Kawasaki M, Inagaki F.
Random PCR-based screening for soluble domains using green fluorescent protein.
Biochem Biophys Res Commun. 280 842-844 (2001)

Yuzawa S, Yokochi M, Hatanaka H, Ogura K, Kataoka M, Miura K, Mandiyan V, Schlessinger J, Inagaki F.
Solution structure of Grb2 reveals extensive flexibility necessary for target recognition.
J Mol Biol. 306 527-537 (2001)

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